Method of treatment of cancers
US-12036259-B2 · Jul 16, 2024 · US
US9839660B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9839660-B2 |
| Application number | US-201013512800-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 29, 2010 |
| Priority date | Nov 30, 2009 |
| Publication date | Dec 12, 2017 |
| Grant date | Dec 12, 2017 |
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The present invention provides a composition comprising Astragali Radix extract as an active ingredient. The composition can increase body energy consumption and muscle metabolism. The present invention also relates to pharmaceutical and food compositions which include a composition comprising the Astragali Radix extract. The pharmaceutical and food compositions also increase body energy consumption and muscle metabolism.
Opening claim text (preview).
The invention claimed is: 1. A method for activating peroxisome proliferator-activated receptor gamma coactivator 1-alpha(PGC1-α) promoter, comprising: parenterally administering to a subject in need of increasing basal metabolic rate a composition comprising an active component and a pharmaceutically acceptable carrier, wherein the active component consists of an astragali radix powdered freeze-dried extract, wherein the astragali radix powdered freeze-dried extract content is comprised in an amount of 10-60 wt % based on the total weight of the composition, and wherein the composition promotes production of mitochondria in the subject, wherein the astragali radix powdered freeze-dried extract is prepared by mixing astragali radix with triply distilled water as a ratio of 1:10, extracting the mixture for 3 hours in an extractor and repeating the mixing and extracting 2 times, filtering the resulting extract through a filter paper, concentrating the filtrate under reduced pressure, and freeze-drying the concentrate to obtain dry powder of astragali radix extract. 2. The method according to claim 1 , wherein parenteral administration comprises injection. 3. The method according to claim 1 , wherein the pharmaceutically acceptable carrier comprises a diluent. 4. The method according to claim 3 , wherein the diluent is lactose.
Drugs for disorders of the metabolism (of the blood or the extracellular fluid A61P7/00) · CPC title
Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] · CPC title
Food compositions, function of food ingredients or processes for food or foodstuffs · CPC title
Drugs for disorders of the nervous system · CPC title
Plant extracts, their artificial duplicates or their derivatives · CPC title
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