Core-shell nanoparticles comprising same element of different isotopes

Patent metadata

Field	Value
Publication number	US-9835628-B2
Application number	US-201514695083-A
Country	US
Kind code	B2
Filing date	Apr 24, 2015
Priority date	Apr 24, 2014
Publication date	Dec 5, 2017
Grant date	Dec 5, 2017

Abstract

A core-shell nanoparticle is provided that includes a core comprising a first isotope of an element; an isolation layer surrounding the core; and a shell layer surrounding the isolation layer, wherein the shell layer comprises a second isotope of the element, with the first isotope being different than the second isotope. Methods are also provided for forming such core-shell nanoparticles.

First claim

What is claimed:

1. A core-shell nanoparticle, comprising:
a core comprising a first isotope of silver;
an isolation layer surrounding the core; and
a shell layer surrounding the isolation layer, wherein the shell layer comprises a second isotope of silver, with the first isotope being different than the second isotope.

2. The nanoparticle as in claim 1 , wherein the isolation layer comprises a material that is substantially free from the element.

3. The nanoparticle as in claim 1 , wherein the first isotope is 107 Ag, and wherein the second isotope is 109 Ag.

4. The nanoparticle as in claim 1 , wherein the first isotope is 109 Ag, and wherein the second isotope is 107 Ag.

5. The nanoparticle as in claim 1 , wherein the isolation layer comprises gold.

6. The nanoparticle as in claim 1 , wherein the isolation layer comprises silicon.

7. The nanoparticle as in claim 6 , wherein the isolation layer comprises silicon dioxide.

8. The nanoparticle as in claim 1 , further comprising:
a second isolation layer on the shell layer; and
a second shell layer on the second isolation layer, wherein the second shell layer comprises a third isotope of silver, with the third isotope being different than the first isotope, the second isotope, or both.

9. The nanoparticle as in claim 8 , further comprising:
a third isolation layer on the second shell layer; and
a third shell layer on the third isolation layer, wherein the third shell layer comprises a fourth isotope of silver, with the fourth isotope being different than the first isotope, the second isotope, and/or the third isotope.

10. The nanoparticle as in claim 1 , further comprising:
a polymeric outer layer positioned to define an outer surface on the nanoparticle.

11. The nanoparticle as in claim 10 , wherein the polymeric outer layer comprises a polyvinylpyrrolidone-based polymer.

12. The nanoparticle as in claim 10 , wherein the polymeric outer layer comprises citrate.

Assignees

• Univ South Carolina

Inventors

• Lead Jamie
• Merrifield Ruth

Classifications

• B22F1/17

  Metallic particles coated with metal · CPC title

• B22F1/145

  Chemical treatment, e.g. passivation or decarburisation · CPC title

• B22F1/054

  Nanosized particles · CPC title

• B01J2235/30

  Scanning electron microscopy; Transmission electron microscopy · CPC title

• B01J2235/00

  Indexing scheme associated with group B01J35/00, related to the analysis techniques used to determine the catalysts form or properties · CPC title