Method for producing useful metabolite from filamentous fungus

US9834796B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9834796-B2
Application numberUS-201214343404-A
CountryUS
Kind codeB2
Filing dateAug 6, 2012
Priority dateSep 7, 2011
Publication dateDec 5, 2017
Grant dateDec 5, 2017

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  1. Title

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  2. Abstract

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  5. First independent claim

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Abstract

Official abstract text for this publication.

The present invention relates to a method for producing useful metabolites such as shikimic acid from filamentous fungus. The useful metabolites can be produced by a production method involving a step of inhibiting the growth of the filamentous fungus, specifically by applying a stimulus of light having a center wavelength shorter than 570 nm to the filamentous fungus, to increase the content of the useful metabolite in a hypha of the filamentous fungus.

First claim

Opening claim text (preview).

The invention claimed is: 1. A method for producing useful metabolites comprising a process of suppressing the growth of filamentous fungi by applying light stimulation to filamentous fungi, and a process of extracting useful metabolites from filamentous fungi; wherein the useful metabolite is shikimic acid, and wherein the light stimulation is a stimulus of light having a center wavelength shorter than 570 nm, thereby the biosynthetic pathway of aromatic amino acids is blocked after shikimic acid is biosynthesized. 2. The method according to claim 1 , wherein the light stimulation is a stimulus of blue light and/or a stimulus of light having a photon flux density not less than 11 μmol m −2 s −1 . 3. The method according to claim 1 , wherein the light stimulation is applied with intermittent irradiation. 4. The method according to claim 1 , wherein the extraction is carried out from filamentous fungi in mycelial state. 5. The method according to claim 1 , wherein the filamentous fungus is Pleurotus ostreatus. 6. The method according to claim 1 , wherein the extraction comprises separation into a water layer and an organic layer using an organic solvent and water, and collection of the water layer.

Assignees

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Classifications

  • Antineoplastic agents · CPC title

  • Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves · CPC title

  • Fungi (culture of mushrooms A01G18/00; as new plants A01H15/00); Culture media therefor · CPC title

  • C12P7/42Primary

    Hydroxy-carboxylic acids · CPC title

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What does patent US9834796B2 cover?
The present invention relates to a method for producing useful metabolites such as shikimic acid from filamentous fungus. The useful metabolites can be produced by a production method involving a step of inhibiting the growth of the filamentous fungus, specifically by applying a stimulus of light having a center wavelength shorter than 570 nm to the filamentous fungus, to increase the content o…
Who is the assignee on this patent?
Kojima Masanobu, Fujii Hiroshi, Univ Shinshu
What technology area does this patent fall under?
Primary CPC classification C12P7/42. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Dec 05 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).