Piperidinone carboxamide azaindane CGRP receptor antagonists
US-9499545-B2 · Nov 22, 2016 · US
US9833448B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9833448-B2 |
| Application number | US-201615293569-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 14, 2016 |
| Priority date | Nov 12, 2010 |
| Publication date | Dec 5, 2017 |
| Grant date | Dec 5, 2017 |
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The present invention is directed to piperidinone carboxamide azaindane derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
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What is claimed is: 1. A method of treating migraine in a mammalian patient in need of such treatment which method comprises administering to the patient a therapeutically effective amount of a pharmaceutical composition comprising the compound of Formula II: or a pharmaceutically acceptable salt thereof.
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