Transcutaneous analyte sensor

Patent metadata

Field	Value
Publication number	US-9833176-B2
Application number	US-201213547952-A
Country	US
Kind code	B2
Filing date	Jul 12, 2012
Priority date	Jul 13, 2004
Publication date	Dec 5, 2017
Grant date	Dec 5, 2017

Abstract

The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

First claim

What is claimed is:

1. A transcutaneous system for measuring an analyte concentration in a host, the system comprising:
a sensor adapted for transcutaneous placement through a skin of a host, the sensor comprising a first terminal end and a second terminal end, the first terminal end opposite from the second terminal end;
a housing configured to support the sensor during a period of transcutaneous insertion; and
an applicator comprising a needle configured for inserting the sensor into the skin of the host, wherein the needle is configured to insert the first terminal end of the sensor into the host and slide back over the second terminal end of the sensor, wherein the needle is configured to be released from the housing during a period of continuous transcutaneous placement, wherein the needle is fully enclosed around a longitudinal section of the sensor, wherein the first terminal end and second terminal end of the sensor are sized to fully reside within the needle, and wherein the first terminal end and the second terminal end have substantially same dimensions.

2. The system of claim 1 , further comprising sensor electronics configured to releasably attach to the housing during the period of transcutaneous insertion.

3. The system of claim 1 , wherein the time period of transcutaneous insertion is at least about 3 days.

4. A transcutaneous system for measuring an analyte concentration in a host, the system comprising:
a non-planar sensor adapted for transcutaneous placement through a skin of a host, the sensor comprising a first terminal end and a second terminal end, wherein a portion of the second terminal end of the sensor is configured to provide connectivity between the sensor and sensor electronics; and
an applicator comprising a needle configured for inserting the sensor into the skin of the host, wherein the system is configured such that the needle is capable of inserting the first terminal end of sensor into the host and sliding back over the second terminal end of the sensor, thereby releasing the sensor from the needle.

5. The system of claim 4 , wherein the non-planar sensor comprises a working electrode formed from a wire.

6. The system of claim 5 , wherein the wire has a diameter of less than about 0.010 inches.

7. The system of claim 4 , further comprising a housing configured to support the sensor during a period of transcutaneous insertion, wherein the needle is configured to be released from the housing during the period of continuous transcutaneous insertion, wherein the first terminal end and the second terminal end of the sensor are sized to fully reside within the needle.

8. The system of claim 4 , wherein the sensor comprises a first electrode formed from a wire, an insulator fully surrounding at least a portion of the wire, and a second electrode fully surrounding at least a portion of the insulator; wherein a portion of the second terminal end has a first electrode connection comprising an exposed electroactive surface of the wire and a second electrode connection on an exposed electroactive surface of the second electrode.

9. The system of claim 4 , wherein the portion of the second terminal end comprises a first electrode connection and a second electrode connection, and wherein the first electrode connection and the second electrode connection are longitudinally separated along a longitudinal axis of the sensor.

10. A transcutaneous system for measuring an analyte concentration in a host, the system comprising:
a sensor adapted for transcutaneous placement through a skin of a host, the sensor comprising a first electrode formed from a wire, an insulator that fully surrounds at least a portion of the wire and a second electrode that fully surrounds at least a portion of the insulator; and
an applicator comprising a needle configured for inserting the sensor into the skin of the host; wherein the system is configured such that the needle is capable of inserting at least the first electrode of the sensor into the host, sliding back over the first electrode and the second electrode of the sensor, and thereby releasing the sensor from the needle, wherein a portion of a terminal end of the sensor has a first electrode connection comprising an exposed electroactive surface of the wire and a second electrode connection on an exposed electroactive surface of the second electrode.

11. The system of claim 10 , wherein the wire has a diameter of less than about 0.010 inches.

12. The system of claim 10 , wherein the wire has a diameter of less than about 0.005 inches.

13. A transcutaneous system for measuring an analyte concentration in a host, the system comprising:
a sensor adapted for transcutaneous placement through a skin of a host, the sensor comprising a first terminal end and a second terminal end, wherein the first terminal end and the second terminal end have substantially same dimensions; and
an applicator comprising a needle configured for inserting the sensor into the skin of the host;
wherein the system is configured such that the needle is configured to insert the first terminal end of the sensor into the host, slide back over the second terminal end of the sensor, and release the sensor from the needle, wherein the needle fully encloses around a longitudinal section of the sensor, wherein a portion of the second terminal end comprises a first electrode connection and a second electrode connection, and wherein the first electrode connection and the second electrode connection are longitudinally separated along a longitudinal axis of the sensor.

14. The system of claim 13 , wherein the sensor is formed from a wire.

15. The system of claim 13 , wherein the sensor comprises a circular cross-section.

Assignees

• Brister Mark
• Neale Paul V
• Saint Sean
• Petisce James R
• Mcgee Thomas F
• Codd Daniel Shawn
• Petersen David Michael
• Kline Daniel S
• Dexcom Inc

Inventors

• Brister Mark
• Neale Paul V
• Saint Sean
• Petisce James R
• Mcgee Thomas F
• Codd Daniel Shawn
• Petersen David Michael
• Kline Daniel S

Classifications

• A61B5/14514

  using means for aiding extraction of interstitial fluid, e.g. microneedles or suction · CPC title

• A61B5/6833

  Adhesive patches · CPC title

• A61B5/14735

  comprising an immobilised reagent · CPC title

• A61M2005/1585

  Needle inserters · CPC title

• A61M5/14244

  adapted to be carried by the patient, e.g. portable on the body · CPC title