Microbial composition

Patent metadata

Field	Value
Publication number	US-9832995-B2
Application number	US-201214363455-A
Country	US
Kind code	B2
Filing date	Dec 5, 2012
Priority date	Dec 6, 2011
Publication date	Dec 5, 2017
Grant date	Dec 5, 2017

Abstract

A synergistic microbicidal composition containing synergistic combinations of a phenolic compound selected the class consisting of chlorinated phenols, monosubstituted phenols, fused bicyclic phenols, isopropyl methyl catechols and monosubstituted catechols and an antimicrobial alcohol selected from the class consisting of propen-2yl-methyl-cyclohexanols, menthadiene alcohols and substituted cyclohexyl propyl-1,3-diols.

First claim

The invention claimed is:

1. A synergistic microbicidal composition comprising: (a) at least one microbicide selected from the group consisting of 4-chloro-3,5-dimethylphenol, 2-hydroxydiphenylmethane, 4-hydroxydiphenylmethane, 2-cyclopentylphenol, 4-cyclopentylphenol, 3-isopropyl-6-methylbenzene-1,2-diol and 4-tert-butylbenzene-1,2-diol; and (b) 2-methyl-5-(prop-1-en-2-yl)cyclohex-2-enol; wherein a weight ratio of 4-chloro-3,5-dimethylphenol to 2-methyl-5-(prop-1-en-2-yl)cyclohex-2-enol is from 1/0.25 to 1/3.5, a weight ratio of 2-hydroxydiphenylmethane to 2-methyl-5-(prop-1-en-2-yl)cyclohex-2-enol is from 1/0.03 to 1/0.10 or 1/0.15 to 1/1.75, a weight ratio of 4-hydroxydiphenylmethane to 2-methyl-5-(prop-1-en-2-yl)cyclohex-2-enol is from 1/0.1 to 1/4.4, a weight ratio of 2-cyclopentylphenol to 2-methyl-5-(prop-1-en-2-yl)cyclohex-2-enol is from 1/0.05 to 1/0.13 or 1/0.25 to 1/3.5, a weight ratio of 4-cyclopentylphenol to 2-methyl-5-(prop-1-en-2-yl)cyclohex-2-enol is from 1/0.06 to 1/0.19 or 1/0.25 to 1/4.38, a weight ratio of 4-tert-butylbenzene-1,2-diol to 2-methyl-5-(prop-1-en-2-yl)cyclohex-2-enol is from 1/0.03 to 1/0.09 or 1/0.88 to 1/1.75 and a weight ratio of 3-isopropyl-6-methylbenzene-1,2-diol to 2-methyl-5-(prop-1-en-2-yl)cyclohex-2-enol is from 1/0.03 to 1/0.09 or 1/0.88 to 1/1.75.

2. The synergistic microbicidal composition of claim 1 wherein the microbicide is 4-chloro-3,5-dimethylphenol and 2-methyl-5-(prop-1-en-2-yl)cyclohex-2-enol in a weight ratio from 1/0.25 to 1/3.5.

3. A synergistic microbicidal composition comprising: (a) at least one microbicide selected from the group consisting of 3-isopropyl-6-methylbenzene-1,2-diol, 2-hydroxydiphenylmethane, 4-hydroxydiphenylmethane, 4-chloro-3,5-dimethylphenol, 2-cyclopentylphenol and 4-cyclopentylphenol; and (b) (1R,2S,5R)-5-methyl-2-(prop-1-en-2-yl)cyclohexanol; wherein a weight ratio of 3-isopropyl-6-methylbenzene-1,2-diol to (1R,2S,5R)-5-methyl-2-(prop-1-en-2-yl)cyclohexanol is from 1/0.13 to 1/0.83, a weight ratio of 2-hydroxydiphenylmethane to (1R,2S,5R)-5-methyl-2-(prop-1-en-2-yl)cyclohexanol is from 1/0.25 to 1/1.25, a weight ratio of 4-hydroxydiphenylmethane to (1R,2S,5R)-5-methyl-2-(prop-1-en-2-yl)cyclohexanol is from 1/0.19 to 1/1.25, a weight ratio of 4-chloro-3,5-dimethylphenol to (1R,2S,5R)-5-methyl-2-(prop-1-en-2-yl)cyclohexanol is from 1/0.19 to 1/1.25, a weight ratio of 2-cyclopentylphenol to (1R,2S,5R)-5-methyl-2-(prop-1-en-2-yl)cyclohexanol is from 1/0.06 to 1/0.17 or 1/0.25 to 1/2.5 and a weight ratio of 4-cyclopentylphenol to (1R,2S,5R)-5-methyl-2-(prop-1-en-2-yl)cyclohexanol is from 1/0.5 to 1/4.2.

4. A synergistic microbicidal composition comprising: (a) 4-chloro-3,5-dimethylphenol, 2-hydroxydiphenylmethane, 4-hydroxydiphenylmethane, 5,6,7,8-tetrahydronaphthalen-1-ol, 5,6,7,8-tetrahydronaphthalen-2-ol and 4-cyclopentylphenol; and (b) 2-methyl-5-(prop-1-en-2-yl)cyclohexanol; wherein a weight ratio of 4-chloro-3,5-dimethylphenol to 2-methyl-5-(prop-1-en-2-yl)cyclohexanol is from 1/0.17 to 1/2.5, a weight ratio of 2-hydroxydiphenylmethane to 2-methyl-5-(prop-1-en-2-yl)cyclohexanol is from 1/0.04 to 1/0.15 or 1/0.2 to 1/2.5, a weight ratio of 4-hydroxydiphenylmethane to 2-methyl-5-(prop-1-en-2-yl)cyclohexanol is from 1/0.03 to 1/0.08 or 1/0.13 to 1/2.5, a weight ratio of 5,6,7,8-tetrahydronaphthalen-1-ol to 2-methyl-5-(prop-1-en-2-yl)cyclohexanol is from 1/0.19 to 1/2.5, a weight ratio of 5,6,7,8-tetrahydronaphthalen-2-ol to 2-methyl-5-(prop-1-en-2-yl)cyclohexanol is from 1/0.04 to 1/0.13 or 1/0.2 to 1/1.25 and a weight ratio of 4-cyclopentylphenol to 2-methyl-5-(prop-1-en-2-yl)cyclohexanol is from 1/1 to 1/3.1.

5. A method of disinfecting a surface comprising the steps of
a. applying a composition according to any one of the preceding claims on to the surface; and
b. removing the composition from the surface.

Assignees

• Rohm & Haas
• Dow Global Technologies Llc

Inventors

• Cornmell Robert J
• Diehl Megan A
• Golding Stephen
• Harp John R
• Stott Ian P
• Thompson Katherine M
• Truslow Carol L

Classifications

• A61Q17/005

  Antimicrobial preparations · CPC title

• A01N31/16 Primary

  with two or more oxygen or sulfur atoms directly attached to the same aromatic ring system · CPC title

• A01N31/04

  Oxygen or sulfur attached to an aliphatic side-chain of a carbocyclic ring system · CPC title

• A61P31/02

  Local antiseptics · CPC title

• A61Q19/10

  Washing or bathing preparations · CPC title