St2 antigen binding proteins
US-2024368292-A1 · Nov 7, 2024 · US
Anti-IL-6/IL-6R antibodies
US9828430B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9828430-B2 |
| Application number | US-201614993153-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 12, 2016 |
| Priority date | May 13, 2008 |
| Publication date | Nov 28, 2017 |
| Grant date | Nov 28, 2017 |
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- Title
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- Abstract
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Abstract
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This invention provides fully human monoclonal antibodies that recognize the IL-6/IL-6R complex. The invention further provides methods of using such monoclonal antibodies as a therapeutic, diagnostic, and prophylactic.
First claim
Opening claim text (preview).
What is claimed is: 1. An isolated fully human antibody or antigen-binding fragment thereof that binds to IL-6/IL-6R complex (IL-6Rc), wherein said antibody or antigen-binding fragment thereof comprises: (a) a V H CDR1 region comprising the amino acid sequence of SEQ ID NO: 15; (b) a V H CDR2 region comprising the amino acid sequence of SEQ ID NO: 16; (c) a V H CDR3 region comprising the amino acid sequence of SEQ ID NO: 36; (d) a V L CDR1 region comprising the amino acid sequence of SEQ ID NO: 24; (e) a V L CDR2 region comprising the amino acid sequence of SEQ ID NO: 25; and (f) a V L CDR3 region comprising the amino acid sequence of SEQ ID NO: 26. 2. The antibody of claim 1 , wherein said antibody is an IgG isotype. 3. The antibody of claim 1 , wherein said antibody is an IgG1 isotype. 4. A pharmaceutical composition comprising the antibody of claim 1 and a carrier.
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Classifications
Immunosuppressants, e.g. drugs for graft rejection · CPC title
Antineoplastic agents · CPC title
Drugs for immunological or allergic disorders · CPC title
Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] · CPC title
Drugs for disorders of the nervous system · CPC title
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Frequently asked questions
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- What does patent US9828430B2 cover?
- This invention provides fully human monoclonal antibodies that recognize the IL-6/IL-6R complex. The invention further provides methods of using such monoclonal antibodies as a therapeutic, diagnostic, and prophylactic.
- Who is the assignee on this patent?
- Novimmune Sa, Novimmune Sa
- What technology area does this patent fall under?
- Primary CPC classification C07K16/2866. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Nov 28 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).