Antiperspirant products with protein and antiperspirant salts

Patent metadata

Field	Value
Publication number	US-9827177-B2
Application number	US-201214649946-A
Country	US
Kind code	B2
Filing date	Dec 19, 2012
Priority date	Dec 19, 2012
Publication date	Nov 28, 2017
Grant date	Nov 28, 2017

Abstract

The invention provides antiperspirant formulations comprising a protein and an antiperspirant salt in combination with a cosmetically acceptable carrier, together with methods of making and using these complexes and compositions.

First claim

The invention claimed is:

1. An antiperspirant formulation comprising bovine serum albumin and an antiperspirant salt in combination with a cosmetically acceptable carrier, wherein the antiperspirant salt is a zinc lysine chloride complex.

2. The antiperspirant formulation according to claim 1 , wherein the zinc lysine chloride complex is formed from precursors, wherein the precursors are a zinc ion source, a lysine source, and a chloride source, wherein the chloride source can be part of the zinc ion source, the lysine source, or a chlorine acid.

3. The antiperspirant formulation according to claim 2 , wherein the zinc ion source is selected from the group consisting of zinc oxide, zinc chloride, tetrabasic zinc chloride, zinc carbonate, zinc nitrate, zinc citrate, and zinc phosphate.

4. The antiperspirant formulation according to claim 1 , wherein the zinc lysine chloride complex is made by combining zinc oxide with lysine hydrochloride.

5. The antiperspirant formulation according to claim 1 , wherein the zinc lysine chloride complex is made by combining tetrabasic zinc chloride with lysine, or lysine hydrochloride.

6. The antiperspirant formulation according to claim 1 , wherein a total amount of zinc present in the composition is 0.05 to 10% by weight.

7. The antiperspirant formulation according to claim 1 , wherein the zinc lysine chloride complex is present in an amount of 0.05 to 40% by weight of the composition.

8. The antiperspirant formulation according to claim 1 , wherein a molar ratio of zinc to lysine in the zinc lysine chloride complex is 2:1 to 1:4, or 1:1 to 1:4, or 1:2 to 1:4, or 1:3 to 1:4, or 2:1 to 1:3, or 2:1 to 1:2, or 2:1 to 1:1, or 1:3.

9. The antiperspirant formulation according to claim 1 , wherein the zinc lysine chloride complex is ZnLysine 2 Cl 2 or ZnLysine 3 Cl 2 .

10. The antiperspirant formulation of claim 1 , wherein the zinc-lysine-chloride complex has the formula [Zn(C 6 H 14 N 2 O 2 ) 2 Cl] + Cl − , or has the formula [Zn(C 6 H 14 N 2 O 2 ) 2 Cl] + Cl − in a hydrate form.

11. The antiperspirant formulation of claim 1 wherein the amount of protein in the composition is 0.01-5% by weight of the composition.

12. The antiperspirant formulation of claim 1 wherein the pH of the formulation is 6-8.

13. The antiperspirant formulation of claim 1 wherein the cosmetically acceptable carrier comprises one or more ingredients selected from the group consisting of water-soluble alcohols; glycols; glycerides; medium to long chain organic acids, alcohols and esters; surfactants; additional amino acids; structurants; emollients; fragrances; and colorants.

14. The antiperspirant formulation of claim 1 wherein the composition is in the form of an antiperspirant stick, an aerosol antiperspirant spray, or a liquid roll-on antiperspirant.

15. A method of reducing perspiration, reducing body odor and/or killing bacteria, comprising applying an effective amount of the antiperspirant formulation of claim 1 to skin.

Assignees

• Colgate Palmolive Co

Inventors

• Yuan Shaotang
• Pan Long

Classifications

• A61K8/27 Primary

  Zinc; Compounds thereof · CPC title

• A61Q15/00

  Anti-perspirants or body deodorants (deodorisation of air A61L9/00) · CPC title

• A61K8/44

  Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof · CPC title

• A61K2800/874

  Roll-on · CPC title

• A61K2800/58

  Metal complex; Coordination compounds · CPC title