Nonwoven article grafted with copolymer

Patent metadata

Field	Value
Publication number	US-9821276-B2
Application number	US-201314396764-A
Country	US
Kind code	B2
Filing date	Feb 26, 2013
Priority date	Apr 24, 2012
Publication date	Nov 21, 2017
Grant date	Nov 21, 2017

Abstract

A functionalized nonwoven substrate and methods for preparing the same are described. The functionalized substrates are useful in selectively filtering and removing biological materials, such as biocontaminates, from biological samples.

First claim

The invention claimed is:

1. A copolymer grafted article comprising:
a) a nonwoven substrate, and
b) a grafted copolymer comprising interpolymerized monomer units of
a) 10 to 50 parts by weight of a cationic nitrogen-containing ligand monomer, wherein the cationic nitrogen-containing ligand monomer is selected from the group consisting of quaternary ammonium-containing ligand monomers, guanidinyl-containing ligand monomers, and combinations thereof;
b) 10 to 80 parts by weight of an amide monomer;
c) 10 to 40 parts by weight of an oxy monomer selected from the group consisting of epoxy functional monomer units, alkyl ether functional monomer units, and combinations thereof; and
d) 0 to 30 parts by weight of the poly(alkylene oxide) monomer, wherein the sum of a to d is 100 parts by weight.

2. The copolymer grafted article of claim 1 wherein the cationic nitrogen-containing ligand monomer is of the formula:

where X 1 is —O— or —NR 3 —, where R 3 is H or C 1 -C 4 alkyl-; R 5 is an alkylene, and R Lig is a quaternary ammonium ligand group or a guanidinyl-containing ligand group.

3. The copolymer grafted article of claim 1 wherein the quaternary ammonium monomer is of the formula:

where X 1 is —O— or —NR 3 —, where R 3 is H or C 1 -C 4 alkyl-; and R 5 is an alkylene, each R 4 is independently hydrogen, alkyl, or aryl.

4. The copolymer grafted article of claim 1 wherein the guanidinyl-containing ligand monomer is of the formula:

wherein
R 2 is a (hetero)hydrocarbyl group;
each R 3 is independently H or hydrocarbyl
R 14 is H, C 1 -C 4 alkyl or —N(R 3 ) 2 ;
R 15 is H or hydrocarbyl;
X 1 is —O— or —NR 3 —,
o is 0 or 1, and
n is 1 or 2.

5. The copolymer grafted article of claim 4 wherein R 2 is a divalent (hetero)hydrocarbyl group having 1 to 20 carbon atoms.

6. The copolymer grafted article of claim 4 wherein each R 3 is independently H or a C 1 -C 4 alkyl group.

7. The copolymer grafted article of claim 4 wherein R 15 is H, a C 1 -C 4 alkyl group, or an aryl group.

8. The copolymer grafted article of claim 1 having interpolymerized oxy monomer units of the formula:

wherein:
R 3 is —H or C 1 -C 4 alkyl;
X 1 is —NR 3 —or —O— ; and
R 1 is an epoxy-functional or ether-functional hydrocarbyl group.

9. The copolymer grafted article of claim 1 having interpolymerized oxy monomer units of the formula:

wherein:
R 7 is a (hetero)hydrocarbyl group;
R 3 is —H or C 1 -C 4 alkyl; and
X 1 is —NR 3 — or —O—.

10. The copolymer grafted article of claim 9 wherein R 7 is a hydrocarbyl group.

11. The copolymer grafted article of claim 9 wherein R 7 is a C 1 -C 6 alkylene group.

12. The copolymer grafted article of claim 1 having interpolymerized amide monomer units of the formula:

where
R 3 is —H or C 1 -C 4 alkyl;
Each R 8 is an H, an alkyl or an aryl group,
R 9 and R 10 are alkyl groups, or may be taken together to form a 5 or 6-membered ring.

13. The copolymer grafted article of claim 1 wherein the nonwoven substrate has a tensile strength of at least 4.0 newtons prior to grafting.

14. The copolymer grafted article of claim 1 wherein the nonwoven substrate has a surface area of 15 to 50 m 2 per square meter of nonwoven substrate.

15. The copolymer grafted article of claim 1 wherein the nonwoven substrate has a mean pore size of 1-40 microns according to ASTM F 316-03.

16. The copolymer grafted article of claim 1 wherein the nonwoven substrates have a solidity of less than 20%.

17. The copolymer grafted article of claim 1 wherein the nonwoven substrate is a spunlaid, hydroentangled or a meltblown nonwoven substrate.

18. The copolymer grafted article of claim 1 wherein the weight of the grafted polymer is 0.5 to 3 times the weight of the nonwoven substrate.

19. The copolymer grafted article of claim 1 wherein the nonwoven substrate is prepared from a hydrophobic thermoplastic polyolefin.

20. The copolymer grafted article of claim 1 wherein the graft copolymer is of the formula
-(M NR4+ ) a -(M Oxy ) b -(M Amide ) c ,wherein
-(M NR4+ ) a -represent the residue of the grafted cationic nitrogen-containing ligand monomer having a polymerized monomer units where a is at least 1,
-(M Oxy ) b represents the polymerized oxy monomer units having b polymerized monomer units, where b is at least one;
(M Amide ) c represents the polymerized amide monomer having c polymerized monomer units, where c is at least one.

21. The copolymer grafted article of claim 20 wherein the copolymer is a random copolymer.

22. The copolymer grafted article of claim 20 wherein the copolymer is a block copolymer.

23. The copolymer grafted article of claim 1 wherein the copolymer is uncrosslinked.

24. The copolymer grafted article of claim 1 wherein the nonwoven substrate comprises a single fiber type.

25. The copolymer grafted article of claim 1 wherein the oxy monomer is selected from the group consisting of epoxy functional monomer units, alkyl ether functional (meth)acrylate monomer units, alkyl ether functional (meth)acrylamide monomer units, and combinations thereof.

26. The copolymer grafted article of claim 1 wherein the nonwoven substrate has an effective fiber diameter of about 3 to about 10 micrometers.

27. The copolymer grafted article of claim 26 wherein the nonwoven substrate has an effective fiber diameter of from about 4 to 10 micrometers.

28. A copolymer grafted article comprising:
a) a nonwoven substrate, and
b) a grafted copolymer comprising interpolymerized monomer units of
a) 10 to 50 parts by weight of a cationic nitrogen-containing ligand monomer, wherein the cationic nitrogen-containing ligand monomer is selected from the group consisting of quaternary ammonium-containing ligand monomers, guanidinyl-containing ligand monomers, and combinations thereof;
b) 10 to 80 parts by weight of an amide monomer;
c) 10 to 40 parts by weight of an oxy monomer selected from the group consisting of epoxy functional monomer units, alkyl ether functional monomer units, and combinations thereof; and
d) 0 to 30 parts by weight of the poly(alkylene oxide) monomer, wherein the sum of a to d is 100 parts by weight,

wherein the cationic nitrogen-containing ligand monomer is selected from the group consisting of agmatine containing ligands, guanidine containing ligands, biguanide containing ligands, and combinations thereof.

29. The copolymer grafted article of claim 28 wherein the agmatine containing ligand is an isocyanatoethylmethacrylate-agmatine adduct.

30. A

Assignees

• 3M Innovative Properties Co

Inventors

• Berrigan Michael R
• Hester Jonathan F
• Waller Jr Clinton P
• Weiss Douglas E

Classifications

• D06M14/28

  of macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds · CPC title

• Y10T442/20

  Coated or impregnated woven, knit, or nonwoven fabric which is not [a] associated with another preformed layer or fiber layer or, [b] with respect to woven and knit, characterized, respectively, by a particular or differential weave or knit, wherein the coating or impregnation is neither a foamed material nor a free metal or alloy layer · CPC title

• B01D2323/36

  Introduction of specific chemical groups · CPC title

• D06M14/26

  on to materials of synthetic origin · CPC title

• B01D67/009

  with wave-energy, particle-radiation or plasma · CPC title