Compositions and methods of use of interleukin-10 peptides and anti-interleukin-10 antibodies
US-2016280778-A1 · Sep 29, 2016 · US
Methods of reducing salmonella in poultry
US9821029B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9821029-B2 |
| Application number | US-201514801160-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 16, 2015 |
| Priority date | Aug 2, 2013 |
| Publication date | Nov 21, 2017 |
| Grant date | Nov 21, 2017 |
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Abstract
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Described herein are methods of reducing Salmonella in the intestines of poultry in need thereof by administering to a poultry bird an effective amount of an interleukin-10 peptide or an isolated antibody that specifically binds an interleukin-10 peptide. Administering may be performed within 1 to 4 weeks of harvest of the poultry in order to reduce Salmonella transmission to human consumers. Also included herein are finishing feeds that include an interleukin-10 peptide or an isolated antibody that specifically binds an interleukin-10 peptide.
First claim
Opening claim text (preview).
The invention claimed is: 1. A method of reducing Salmonella in the intestines of poultry in need thereof, comprising administering to a poultry bird an effective amount of an isolated antibody that specifically binds an interleukin-10 peptide, wherein administering is within 1 to 4 weeks of harvest of the poultry, wherein the interleukin-10 peptide is SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5. 2. The method of claim 1 , wherein the poultry bird is a Salmonella incubatory or convalescent carrier. 3. The method of claim 1 , wherein the isolated antibody specifically binds SEQ ID NO: 2, or SEQ ID NO: 3. 4. The method of claim 1 , wherein the poultry is a chicken, a turkey, a duck, a quail, or a pheasant. 5. The method of claim 1 , wherein the poultry is a chicken, and wherein the isolated antibody that specifically binds the interleukin-10 peptide is administered at weeks 3, 4, 5, 6, 7, and/or 8 after hatch. 6. The method of claim 1 , wherein the poultry is a turkey, and wherein the isolated antibody that specifically binds the interleukin-10 peptide is administered at weeks 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21 and/or 22 after hatch. 7. The method of claim 1 , wherein the isolated antibody is administered by injection or oral administration. 8. The method of claim 1 , wherein the isolated antibody is in the form of an avian egg yolk antibody. 9. The method of claim 8 , wherein the isolated antibody specifically binds SEQ ID NO: 2, or SEQ ID NO: 3. 10. The method of claim 1 , wherein the isolated antibody is administered in the form of a poultry feed composition. 11. The method of claim 10 , wherein the poultry feed composition is a finishing feed comprising no added antibiotics. 12. The method of claim 10 , wherein the isolated antibody is present in the poultry feed composition in an amount of 0.15 mg/kg of animal feed to 100 mg/kg of poultry feed.
Assignees
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Classifications
isolated from eggs · CPC title
Antibiotics · CPC title
against proteinaceous materials, e.g. enzymes, hormones, lymphokines · CPC title
comprising antibodies · CPC title
oral/gastrointestinal · CPC title
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- What does patent US9821029B2 cover?
- Described herein are methods of reducing Salmonella in the intestines of poultry in need thereof by administering to a poultry bird an effective amount of an interleukin-10 peptide or an isolated antibody that specifically binds an interleukin-10 peptide. Administering may be performed within 1 to 4 weeks of harvest of the poultry in order to reduce Salmonella transmission to human consumer…
- Who is the assignee on this patent?
- Wisconsin Alumni Res Found, Us Agriculture
- What technology area does this patent fall under?
- Primary CPC classification A61K38/2066. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Nov 21 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 2 related publications on this page (citations in our corpus or others sharing the same primary CPC).