Magnetic resonance imaging (MRI) apparatus and method of processing MR image

Patent metadata

Field	Value
Publication number	US-9818212-B2
Application number	US-201514886657-A
Country	US
Kind code	B2
Filing date	Oct 19, 2015
Priority date	Oct 21, 2014
Publication date	Nov 14, 2017
Grant date	Nov 14, 2017

Abstract

A magnetic resonance imaging (MRI) apparatus and a method of processing an MR image are provided. The MRI apparatus includes a scanner configured to acquire a first image that is a T1-weighted image and a second image that is a fluid attenuated inversion recovery (FLAIR) image by performing an MRI scan on a brain. The MRI apparatus further includes an image processor configured to determine a white matter region in the second image based on the first image and the second image, and detect a white matter hyperintensity (WMH) region in the determined white matter region. The MRI apparatus further includes an output interface configured to display the detected WMH region and a change in the WMH region over time.

First claim

What is claimed is:

1. A magnetic resonance imaging (MRI) apparatus comprising:
a scanner configured to:
acquire, at a first time point, a first image that is a T1-weighted image and a second image that is a fluid attenuated inversion recovery (FLAIR) image by performing a first MRI scan on a brain; and
acquire, at a second time point, the first image and the second image by performing a second MRI scan on the brain;

an image processor configured to:
determine a white matter region in the second image, based on the first image and the second image; and
detect a white matter hyperintensity (WMH) region in the determined white matter region; and

an output interface configured to display the detected WMH region and a generation and a loss of the detected WMH region over time between the first time point and the second time point.

2. The MRI apparatus of claim 1 , wherein the output interface is further configured to indicate portions where the WMH region is generated and lost at corresponding locations in the second image.

3. The MRI apparatus of claim 1 , wherein the output interface is further configured to:
display the second image in a first region of a screen; and
display, as numerical values, a volume of the WMH region and an amount of change in the WMH region over time, in a second region of the screen.

4. The MRI apparatus of claim 1 , wherein the generation and the loss of the WMH region over time comprises a change over time in the WMH region in at least one among frontal, parietal, temporal, and occipital lobes.

5. The MRI apparatus of claim 1 , further comprising an input interface configured to receive an input selecting at least one among frontal, parietal, temporal, and occipital lobes.

6. The MRI apparatus of claim 5 , wherein the output interface is further configured to display a change over time in the WMH region in the selected at least one among frontal, parietal, temporal, and occipital lobes.

7. The MRI apparatus of claim 1 , wherein the image processor is further configured to:
generate a blended image by performing a weighted sum on the first image and the second image; and
determine the white matter region based on the blended image.

8. The MRI apparatus of claim 1 , wherein the image processor is further configured to normalize an intensity of an image signal in each of the second image acquired at the first time point and the second image acquired at the second time point.

9. The MRI apparatus of claim 8 , wherein the image processor is further configured to normalize the intensity of the image signal, based on an intensity of an image signal in a gray matter region in each of the second image acquired at the first time point and the second image acquired at the second time point.

10. A method of processing a magnetic resonance (MR) image, the method comprising:
acquiring, at a first time point, a first image that is a T1-weighted image and a second image that is a fluid attenuated inversion recovery (FLAIR) image by performing a first magnetic resonance imaging (MRI) scan on a brain;
acquiring, at a second time point, the first image and the second image by performing a second MRI scan on the brain;
determining a white matter region in the second image, based on the first image and the second image;
detecting a white matter hyperintensity (WMH) region in the determined white matter region; and
displaying the detected WMH region and a generation and a loss of the detected WMH region over time between the first time point and the second time point.

11. The method of claim 10 , wherein the displaying comprises indicating portions where the WMH region is generated and lost at corresponding locations in the second image.

12. The method of claim 10 , wherein the displaying comprises:
displaying the second image in a first region of a screen; and
displaying, as numerical values, a volume of the WMH region and an amount of change in the WMH region over time, in a second region of the screen.

13. The method of claim 10 , further comprising receiving an input selecting at least one among frontal, parietal, temporal, and occipital lobes.

14. The method of claim 13 , wherein the displaying comprises displaying a change over time in the WMH region in the selected at least one among frontal, parietal, temporal, and occipital lobes.

15. The method of claim 10 , wherein the determining comprises:
generating a blended image by performing a weighted sum on the first image and the second image; and
determining the white matter region, based on the blended image.

16. The method of claim 15 , wherein the determining further comprises:
classifying tissues in the blended image, the tissues comprising another white matter region;
generating a white matter region image comprising the other white matter region; and
overlaying the whiter matter region image over the second image to determine the white matter region in the second image.

17. The method of claim 10 , wherein the detecting comprises normalizing an intensity of an image signal in each of the second image acquired at the first time point and the second image acquired at the second time point.

18. The method of claim 17 , wherein the normalizing comprises normalizing the intensity of the image signal, based on an intensity of an image signal in a gray matter region in each of the second image acquired at the first time point and the second image acquired at the second time point.

Assignees

• Samsung Electronics Co Ltd

Inventors

• Jeon Seun
• Park Jun-Sung
• Lee Jong-Min
• Lee Jun-Ki

Classifications

• G06T2207/10088

  Magnetic resonance imaging [MRI] · CPC title

• A61B5/0042

  for the brain · CPC title

• G06T2207/30016

  Brain · CPC title

• G06T11/60 Primary

  Creating or editing images; Combining images with text · CPC title

• G06T7/11

  Region-based segmentation · CPC title