Compositions comprising fibrous polypeptides and polysaccharides

US9815874B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9815874-B2
Application numberUS-201615011738-A
CountryUS
Kind codeB2
Filing dateFeb 1, 2016
Priority dateNov 26, 2007
Publication dateNov 14, 2017
Grant dateNov 14, 2017

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

Isolated polypeptides are disclosed comprising an amino acid sequence encoding a monomer of a fibrous polypeptide attached to a heterologous polysaccharide binding domain. Composites comprising same, methods of generating same and uses thereof are all disclosed.

First claim

Opening claim text (preview).

What is claimed is: 1. An isolated monomer of a fibrous polypeptide attached to a hyaluronic acid binding domain via a polypeptide bond. 2. The isolated monomer of claim 1 , wherein said fibrous polypeptide is selected from the group consisting of resilin, elastin, spider silk, silk-worm silk, collagen and mussel byssus protein. 3. The isolated monomer of claim 2 , wherein said resilin comprises an amino acid sequence as set forth in SEQ ID NO: 8 or SEQ ID NO: 9. 4. The isolated monomer of claim 3 , further comprising an amino acid sequence as set forth in SEQ ID NOs: 52 or 53. 5. An isolated composite comprising a monomer of a fibrous polypeptide and hyaluronic acid, said monomer being attached to a hyaluronic acid binding domain, the composite not being attached to a solid support. 6. The isolated composite of claim 5 , wherein said fibrous polypeptide is selected from the group consisting of mussel byssus protein, resilin, silkworm silk protein, spider silk protein, collagen, elastin or fragments thereof. 7. The isolated composite of claim 5 , wherein said fibrous polypeptide is resilin.

Assignees

Inventors

Classifications

  • Immunomodulators · CPC title

  • Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] · CPC title

  • Incoherent waves · CPC title

  • for bone diseases, e.g. rachitism, Paget's disease · CPC title

  • from silkworms · CPC title

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What does patent US9815874B2 cover?
Isolated polypeptides are disclosed comprising an amino acid sequence encoding a monomer of a fibrous polypeptide attached to a heterologous polysaccharide binding domain. Composites comprising same, methods of generating same and uses thereof are all disclosed.
Who is the assignee on this patent?
Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd, Collplant Ltd, Collplantltd
What technology area does this patent fall under?
Primary CPC classification C07K14/43581. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Nov 14 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).