Spinal implants with stem cells

Patent metadata

Field	Value
Publication number	US-9814558-B2
Application number	US-201514812126-A
Country	US
Kind code	B2
Filing date	Jul 29, 2015
Priority date	Jul 13, 2011
Publication date	Nov 14, 2017
Grant date	Nov 14, 2017

Abstract

A spinal implant device has a synthetic or metallic or a combination thereof of these materials in an implant body structure and stem cells in a coating, or a sheet, wrap or a membrane wrap applied to surfaces on the implant body structure or alternatively filled with a plug of stem cell laden material. The implant body structure preferably has an aperture or channel. The spinal implant device may include anchoring holes to secure the device to the spinal skeletal structure with fasteners or alternatively can simply be held in place by and between adjacent vertebrae.

First claim

What is claimed is:

1. A method of surgically treating a patient for spinal implant comprises the steps of:
providing a spinal implant in a pre-packaged container, the spinal implant having a stem cell laden coating or wrap, the spinal implant having a synthetic or metallic body structure with an aperture or channel filled with cadaver bone with the coating or wrap on an exterior surface of the body structure of the spinal implant, the coating or wrap being a material laden with stem cells being pre-coated or wrapped at the manufacturing site;
preparing the patient to receive the spinal implant by surgically exposing the area to receive the spinal implant;
removing the spinal implant from the container; and
implanting the spinal implant with the body structure pre-filled with cadaver bone and coated or wrapped in the coating or wrap laden with stem cells.

2. The method of claim 1 further comprises the step of hydrating the stem cell laden coating or wrap in a sterile liquid either before packaging the implant in the container or after removing the implant from the container before implanting.

3. A method of surgically treating a patient for spinal implant comprises the steps of:
providing a spinal implant in a pre-packaged container, the spinal implant having a stem cell laden coating, wrap or membrane, the spinal implant having a synthetic or metallic body structure with an aperture or channel filled with cadaver bone with the coating, wrap or membrane on an exterior surface of the body structure of the spinal implant, the coating, wrap or membrane being a material laden with stem cells being pre-coated or wrapped at the manufacturing site;
preparing the patient to receive the spinal implant by surgically exposing the area to receive the spinal implant;
removing the spinal implant from the container; and
implanting the spinal implant with the body structure pre-filled with cadaver bone and coated or wrapped in the coating, the wrap or the membrane laden with stem cells.

4. The method of claim 3 further comprises the step of hydrating the stem cell laden coating, wrap or membrane in a sterile liquid either before packaging the implant in the container or after removing the implant from the container before implanting.

Assignees

• Vivex Biomedical Inc

Inventors

• Davenport Alan
• Anderson Tracy Scott
• Radcliffe Jeffrey Scott

Classifications

• A61F2002/30593

  hollow · CPC title

• A61L27/3834

  Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells · CPC title

• A61F2002/30912

  made of expanded metal, e.g. diamond mesh or metal nets having lozenge-shaped apertures · CPC title

• A61F2002/30973

  Two joined adjacent layers having complementary interlocking protrusions and recesses · CPC title

• A61F2002/30062

  (bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive · CPC title