Autosampler and gas chromatography system and method including same

Patent metadata

Field	Value
Publication number	US-9810668-B2
Application number	US-201514626222-A
Country	US
Kind code	B2
Filing date	Feb 19, 2015
Priority date	Feb 19, 2015
Publication date	Nov 7, 2017
Grant date	Nov 7, 2017

Abstract

A gas chromatography system includes at least one gas chromatography subsystem including at least one injector port, and an autosampler. The autosampler includes a carousel tray mounted for rotation about a rotation axis and including arcuately extending first and second rows of sample reservoirs, a first sample transfer tower to extract samples from the first row, a second sample transfer tower to extract samples from the second row, and a control system operative to: selectively position the carousel tray relative to the first and second sample transfer towers to align the first and second sample transfer towers with a selected pair of the sample reservoirs of the first and second rows, respectively; draw samples from the selected pair using the first and second sample transfer towers; inject the sample drawn from the first row into the at least one injector port using the first sample transfer tower; and inject the sample drawn from the second row into the at least one injector port using the second sample transfer tower.

First claim

What is claimed:

1. A gas chromatography system comprising:
at least one gas chromatography subsystem including a first injector port and a second injector port;
an autosampler including:
a carousel tray mounted for rotation about a rotation axis, wherein the carousel tray is mounted above the first and second injector ports, and wherein the carousel tray includes:
an arcuately extending first row of sample reservoirs; and
an arcuately extending second row of sample reservoirs;

a first sample transfer tower to extract samples from the first row of sample reservoirs;
a second sample transfer tower to extract samples from the second row of sample reservoirs; and
a control system operative to:
selectively position the carousel tray relative to the first and second sample transfer towers to align the first sample transfer tower with a first sample reservoir in the first row and to align the second sample transfer tower with a second sample reservoir in the second row;
simultaneously draw a first sample from the first sample reservoir using the first sample transfer tower and a second sample from the second sample reservoir using the second sample transfer tower; and sequentially thereafter
simultaneously inject the first sample into the first injector port using the first sample transfer tower and the second sample into the second injector port using the second sample transfer tower.

2. The gas chromatography system of claim 1 including first and second gas chromatography subsystems each including:
a sample injector;
a column fluidly connected to the sample injector; and
a detector fluidly connected to the column;
wherein the sample injector of the first gas chromatography subsystem includes the first injector port and the sample injector of the second gas chromatography subsystem includes the second injector port.

3. The gas chromatography system of claim 1 wherein the control system is operative to draw the first and second samples from the selected pair of the first and second sample reservoirs using the first and second sample transfer towers within less than 50 milliseconds of one another.

4. The gas chromatography system of claim 1 wherein the control system is operative to inject the first and second samples into the first and second injector ports using the first and second sample transfer towers within less than 50 milliseconds of one another.

5. The gas chromatography system of claim 1 wherein the control system is operative to:
selectively reposition the carousel tray relative to the first and second sample transfer towers to align the first and second sample transfer towers with a third sample reservoir in the first row and a fourth sample reservoir in the second row, respectively;
simultaneously draw a third sample from the third sample reservoir using the first sample transfer tower and a fourth sample from the fourth sample reservoir using the second sample transfer tower; and sequentially thereafter
simultaneously inject the third sample into the first injector port using the first sample transfer tower and the fourth sample into the second injector port using the second sample transfer tower.

6. The gas chromatography system of claim 1 wherein the first and second sample transfer towers are fixed in alignment with the first and second injector ports, respectively.

7. The gas chromatography system of claim 1 wherein:
each of the first and second sample transfer towers includes:
a syringe including a needle; and
a syringe actuator; and

the control system is operative to:
drive the needles of the first and second sample transfer towers into the first and second sample reservoirs and to operate the syringes using the associated syringe actuators to draw the first and second samples therefrom; and
drive the needles of the first and second sample transfer towers into the first and second injector ports and to operate the syringes using the associated syringe actuators to inject the first and second samples into the first and second injector ports.

8. The gas chromatography system of claim 7 wherein:
the needle of the first sample transfer tower has a first needle axis;
the needle of the second sample transfer tower has a second needle axis;
the first injector port is aligned with the first needle axis and the second injector port is aligned with the second needle axis; and
the autosampler is configured to position the carousel between the first and second injector ports and the needles of the first and second transfer towers such that a sample reservoir in the first row is aligned with the first needle axis and a sample reservoir in the second row is aligned with the second needle axis.

9. The gas chromatography system of claim 1 wherein the second row is located radially between the first row and the rotation axis of the carousel tray.

10. A method for performing gas chromatography, the method comprising:
providing a gas chromatography system including:
at least one gas chromatography subsystem including a first injector port and a second injector port;
an autosampler including:
a carousel tray mounted for rotation about a rotation axis, wherein the carousel tray is mounted above the first and second injector ports, and wherein the carousel tray includes:
an arcuately extending first row of sample reservoirs; and
an arcuately extending second row of sample reservoirs;

a first sample transfer tower to extract samples from the first row of sample reservoirs;
a second sample transfer tower to extract samples from the second row of sample reservoirs; and
a control system;

selectively positioning the carousel tray relative to the first and second sample transfer towers to align the first sample transfer tower with a first sample reservoir in the first row and to align the second sample transfer tower with a second sample reservoir in the second row;
simultaneously drawing a first sample from the first sample reservoir using the first sample transfer tower and a second sample from the second sample reservoir using the second sample transfer tower; and sequentially thereafter
simultaneously injecting the first sample into the first injector port using the first sample transfer tower and the second sample into the second injector port using the second sample transfer tower.

11. The method of claim 10 wherein:
the gas chromatography system includes first and second gas chromatography subsystems each including:
a sample injector;
a column fluidly connected to the sample injector; and
a detector fluidly connected to the column;
wherein the sample injector of the first gas chromatography subsystem includes the first injector port and the sample injector of the second gas chromatography subsystem includes the second injector port.

12. The method of claim 10 including drawing the first and second samples from the first and second sample reservoirs using the first and second sample transfer towers within less than 50 milliseconds of one another.

13. The method of claim 10 including injecting the first and second samples into the first and second injector ports using the first and second sample transfer towers within less than 50 milliseconds of one another.

14. The method of claim 10 including:
selectively repositioning the carousel tray relative to the first and second sample transfer towers to align the first and second sample transfer towers with a third sample reservoir in the first row and a fourth sample reservoir in the second row, respectively;
simultaneously drawing a third sample from the third sample reservoir using the first sample transfer tow

Assignees

• Perkinelmer Health Sci Inc

Inventors

• Neal Timothy

Classifications

• G01N2035/0441

  for samples · CPC title

• G01N35/1079

  with means for piercing stoppers or septums · CPC title

• G01N30/24 Primary

  Automatic injection systems · CPC title

• G01N35/1011

  Control of the position or alignment of the transfer device · CPC title

• G01N35/1095

  for supplying the samples to flow-through analysers (for a specific analyser see relevant groups, e.g. under G01N15/00, G01N21/00, G01N27/00, G01N30/00, H01J49/00) · CPC title