Nucleic acid detection and quantification method and compositions
US-2024294993-A1 · Sep 5, 2024 · US
US9810609B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9810609-B2 |
| Application number | US-201414765009-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 28, 2014 |
| Priority date | Jan 31, 2013 |
| Publication date | Nov 7, 2017 |
| Grant date | Nov 7, 2017 |
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Apparatus for transferring biological material onto storage media, said apparatus comprising a powered hand held device including a powered hammer arrangement, the apparatus further comprising an anvil arrangement and a storage media accepting area between the hammer and the anvil, the apparatus being operable such that in use the storage media is repeatedly compressed between the hammer and the anvil by blows from the hammer.
Opening claim text (preview).
The invention claimed is: 1. An apparatus for transferring a biological material onto a storage media, said apparatus comprising a powered hand held device including a powered hammer arrangement, said apparatus further comprising an anvil arrangement and a storage media accepting area in the form of a slot between said hammer arrangement and said anvil arrangement, the apparatus being operable such that in use the storage media in a form of a sample collection card is repeatedly compressed between the hammer and the anvil by blows from the hammer. 2. The apparatus according to claim 1 , wherein the anvil is adjustable in position relative the hammer. 3. The apparatus according to claim 2 , wherein the storage media is held between the anvil and the hammer or a portion of the apparatus adjacent the hammer. 4. The apparatus according to claim 1 , wherein the hammer includes a moving portion, having a repeatable path of powered motion, and a head portion generally in engagement with the storage media, and said compression is achieved by striking of the head portion by the moving portion. 5. The apparatus according to claim 4 , wherein the repeatable path of powered motion is a reciprocating motion. 6. The apparatus according to claim 4 , wherein the moving portion is powered to move at between 1 and 100 reciprocations per second, more preferably, about 60 reciprocations per second. 7. The apparatus according to claim 1 , wherein the velocity of the moving portion is adjustable to vary a media compression force. 8. The apparatus according to claim 1 , wherein the anvil is detachable from the device. 9. The apparatus according to claim 1 , wherein the device is a battery powered percussive tool including the hammer. 10. The apparatus according to claim 9 , wherein the tool includes a handle and an operating switch, and a head portion including the hammer, to which is fitted the anvil. 11. A method for transferring a biological material onto a storage media in a form of a sample collection card, the method comprising: a) providing a powered hammer and an anvil; b) placing the storage media on each side of a biological sample; c) placing the storage media and the biological sample in a storage media accepting area in a form of a slot between the hammer and the anvil; and d) repeatedly impacting the hammer toward the anvil with sufficient blows and a sufficient number of times to transfer the biological material from the sample to the storage media. 12. The method according to claim 11 wherein, step d) includes at least one of the following: i) impacting at 1 to 100 blows per second; and ii) impacting for between 1 and 10 seconds. 13. A kit comprising: an apparatus for transferring a biological material onto a storage media in a form of a sample collection card, said apparatus comprising a powered hand held device including a powered hammer arrangement, the apparatus further comprising an anvil arrangement and a storage media accepting area in a form of a slot between said hammer arrangement and said anvil arrangement, the apparatus being operable such that in use the storage media is repeatedly compressed between the hammer and the anvil by blows from the hammer; and the storage media providing storage for the biological material transferred thereto by the apparatus.
Means for packing or storing viable microorganisms (casings for storing cell samples A61B10/0096, preservation of living parts of the human or animal body A01N1/10) · CPC title
Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor · CPC title
Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay (C12Q1/6804 takes precedence) · CPC title
involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising (microtomes G01N1/06; pulverising in general B02C; mixing in general B01F) · CPC title
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