Application of click chemistry for signal amplification in IHC and ISH assays
US-12517132-B2 · Jan 6, 2026 · US
US9809609B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9809609-B2 |
| Application number | US-201213461642-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 1, 2012 |
| Priority date | Dec 27, 2005 |
| Publication date | Nov 7, 2017 |
| Grant date | Nov 7, 2017 |
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The present invention provides a benzoazepine compound represented by following general formula (1): or a salt thereof, wherein R represents a hydrogen atom, a hydroxy group optionally protected with a protecting group, etc., R 1 represents a hydrogen atom or hydroxy-protecting group, and X represents an oxygen atom or a sulfur atom. The benzoazepine compound of the present invention and salts thereof have high solubility in water, and can be suitably used for injections.
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The invention claimed is: 1. A benzoazepine compound represented by formula (1) or a salt thereof, wherein R represents a hydrogen atom, a hydroxy group optionally protected with a protecting group, a mercapto group optionally protected with a protecting group, or an amino group optionally protected with one or two protecting groups; R 1 represents a hydrogen atom or…
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