Method and magnetic resonance system for magnetic resonance thermometry

Patent metadata

Field	Value
Publication number	US-9808176-B2
Application number	US-201414220427-A
Country	US
Kind code	B2
Filing date	Mar 20, 2014
Priority date	Mar 20, 2013
Publication date	Nov 7, 2017
Grant date	Nov 7, 2017

Abstract

In magnetic resonance (MR) thermometry, first and second magnetic resonance data that are acquired sequentially, from which a phase shift is determined between a measurement phase and a reference phase. In a first region of an examined person, the measurement phase is determined from the second magnetic resonance data and the reference phase is determined from the first magnetic resonance data. In a second region of the examined person, both the reference phase and measurement phase are determined from the second magnetic resonance data. Techniques for reference-based magnetic resonance thermometry and reference-free magnetic resonance thermometry can be applied.

First claim

I claim as my invention:

1. A method for magnetic resonance (MR) thermometry of a patient, comprising:
operating an MR data acquisition unit, in which the patient is situated, to acquire first MR data from the patient at a first point in time;
operating said MR data acquisition unit in which said patient is situated to acquire second MR data from the patient at a second point in time that occurs after said first point in time;
providing said first MR data and said second MR data to a computerized processor and, in said processor, automatically determining a temperature of a first region of the patient by determining a phase shift between said second MR data in said first region, as a measurement phase, and said first MR data in said first region, as a reference phase;
in said processor, automatically determining a temperature in a second region of the patient, which is different from said first region, by determining a phase shift between said second MR data in said second region, as a measurement phase, and said second MR data in a third region of the patient that is different from said first region, and that is situated adjacent to said second region, as a reference phase; and
making the temperature determined in at least one of said first region or said second region available at an output of said processor in electronic form.

2. A method as claimed in claim 1 comprising operating said MR data acquisition unit with said patient situated therein, prior to said first point in time, to acquire a plurality of sets of additional MR data from the patient; and
providing said sets of additional MR data to said processor and, in said processor, establishing said first region and said second region and said third region from said sets of additional MR data.

3. A method as claimed in claim 2 comprising, in said processor:
determining a spatially resolved first temperature curve for said sets of additional MR data by determining a phase shift between each individual set of additional MR data, as a measurement phase, and defined data among said additional MR data, as a reference phase;
determining a spatially resolved second temperature curve for said sets of additional MR data by determining a phase shift between a same region in each individual additional MR data set, as a measurement phase, and a region adjacent to said same region in each individual set of additional MR data, as a reference phase; and
establishing said first region and said second region and said third region dependent on a spatially resolved evaluation of said first temperature curve and said second temperature curve.

4. A method as claimed in claim 3 comprising:
allowing no introduction of heat into said patient during acquisition of said sets of additional MR data; and
determining said first region as at least one region of the patient for which said first temperature curve is temperature-stable; and
determining said second region as at least one region of the patient for which said second temperature curve is temperature-stable.

5. A method as claimed in claim 2 comprising establishing said first and second regions in said processor by:
segmenting said sets of additional MR data to segment selected anatomical regions therein, as segmented regions; and
establishing said first region and said second region and said third region for said segmented regions.

6. A method as claimed in claim 1 comprising, in said processor:
establishing said first region as at least one anatomical region of the patient that exhibits no significant intra-fraction motion; and
establishing said second region as a region of the patient comprising at least one anatomical region that exhibits significant intra-fraction motion.

7. A method as claimed in claim 1 comprising, in said processor:
determining said temperature in said first region using a reference-based thermometry technique; and
determining said temperature in said second region using a reference-free thermometry technique.

8. A method as claimed in claim 1 comprising:
acquiring a respiratory signal from the patient situated in the MR data acquisition unit; and
acquiring at least one of said first MR data and said second MR data dependent on a breathing trigger identified in said respiratory signal.

9. A magnetic resonance (MR) apparatus comprising:
an MR data acquisition unit configured to receive a patient therein;
a control unit configured to operate the MR data acquisition unit, while the patient is situated therein, to acquire first MR data from the patient at a first point in time;
said control unit being configured to operate said MR data acquisition unit, while said patient is situated therein, to acquire second MR data from the patient at a second point in time that occurs after said first point in time;
a computerized processor provided with said first MR data and said second MR data, said processor being configured to automatically determine a temperature of a first region of the patient by determining a phase shift between said second MR data in said first region, as a measurement phase, and said first MR data in said first region, as a reference phase;
said processor being configured to automatically determine a temperature in a second region of the patient, which is different from said first region, by determining a phase shift between said second MR data in said second region, as a measurement phase, and said second MR data in a third region of the patient that is different from said first region, and that is situated adjacent to said second region, as a reference phase; and
said processor being configured to make the temperature determined in at least one of said first region or said second region available at an output of said processor in electronic form.

Assignees

• Gross Patrick
• Siemens Ag

Inventors

• Gross Patrick

Classifications

• A61B5/055 Primary

  involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging · CPC title

• G01R33/4804

  Spatially selective measurement of temperature or pH · CPC title

• A61B5/01

  Measuring temperature of body parts {; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue} (clinical contact thermometers G01K13/20) · CPC title

• G01R33/48

  NMR imaging systems · CPC title