Anterior ocular segment optical coherence tomographic imaging device and anterior ocular segment optical coherence tomographic imaging method

Patent metadata

Field	Value
Publication number	US-9808152-B2
Application number	US-201615179511-A
Country	US
Kind code	B2
Filing date	Jun 10, 2016
Priority date	Jun 11, 2015
Publication date	Nov 7, 2017
Grant date	Nov 7, 2017

Abstract

An anterior ocular segment optical coherence tomographic imaging device and an anterior ocular segment optical coherence tomographic imaging method that can accurately analyze the shape of a crystalline lens by identifying the boundary of each layer of the crystalline lens in a tomographic image of an anterior ocular segment of a subject's eye, which is taken by optical coherence tomography. A layer boundary detector calculates brightness gradients from brightness values in a tomographic image of an anterior ocular segment of a subject's eye, which is taken by optical coherence tomography, in a depth direction of the tomographic image from a cornea to a retina, detect edges b 1 , b 2 , b 3 , and b 4 that are larger than a predetermined threshold, and identify a boundary of each layer of the crystalline lens L from positions of the edge b 1 , b 2 , b 3 , and b 4.

First claim

What is claimed is:

1. An anterior ocular segment optical coherence tomographic imaging device for taking a tomographic image of an anterior ocular segment including a crystalline lens of a subject's eye using optical coherence, the device comprising a layer boundary detector configured to calculate brightness gradients from brightness values in a depth direction of the tomographic image from a cornea to a retina, detect an edge that is larger than a predetermined threshold, and identify a boundary of each layer of the crystalline lens from position of the edge, and trace boundary faces between a crystalline lens front surface and a cortex lentis, between a crystalline lens back surface and the cortex lentis, and between the nucleus lentis and the cortex lentis in the tomographic image.

2. The anterior ocular segment optical coherence tomographic imaging device according to claim 1 , wherein the layer boundary detector is configured to identify a position of a falling edge of the brightness gradient in a region on a front face-side of the crystalline lens as a front surface of the nucleus lentis, and a position of a rising edge of the brightness gradient in a region on a back face-side of the crystalline lens as a back surface of the nucleus lentis.

3. The anterior ocular segment optical coherence tomographic imaging device according to claim 1 , further comprising a tomographic image corrector configured to correct a distortion caused by refraction at the boundary of each layer of the crystalline lens by tracking a ray based on information on a refractive index of each layer of the crystalline lens in the tomographic image.

4. The anterior ocular segment optical coherence tomographic imaging device according to claim 1 , further comprising a first opacity detector configured to determine opacity of the crystalline lens based on the number of edges detected by the layer boundary detector.

5. The anterior ocular segment optical coherence tomographic imaging device according to claim 1 , further comprising a second opacity detector configured to determine opacity of the crystalline lens by determining whether or not a sum and/or an average of the brightness values in the layer detected in the tomographic image is larger than a predetermined threshold.

6. The anterior ocular segment optical coherence tomographic imaging device according to claim 4 , further comprising a second opacity detector configured to determine opacity of the crystalline lens by determining whether or not a sum and/or an average of the brightness values in the layer detected in the tomographic image is larger than a predetermined threshold.

7. An optical coherence tomographic imaging method for taking a tomographic image of an anterior ocular segment including a crystalline lens of a subject's eye by optical Coherence, the method comprising a layer boundary detection step of calculating brightness gradients from brightness values in a depth direction of the tomographic image from a cornea to a retina, detecting an edge that is larger than a predetermined threshold, and identifying a boundary of each layer of the crystalline lens as a position of the edge, and trace boundary faces between a crystalline lens front surface and a cortex lentis, between a crystalline lens back surface and the cortex lentis, and between the nucleus lentis and the cortex lentis in the tomographic image.

8. The optical coherence tomographic imaging method according to claim 7 , wherein the layer boundary detection step identifies a position of a falling edge of the brightness gradient in a region on a front face-side of the crystalline lens as a front surface of the nucleus lentis, and a position of a rising edge of the brightness gradient in a region on a back face-side of the crystalline lens as a back surface of the nucleus lentis.

9. The optical coherence tomographic imaging method according to claim 7 , further comprising a tomographic image correction step of correcting a distortion caused by refraction at the boundary of each layer of the crystalline lens by tracking a ray based on information on a refractive index of each layer of the crystalline lens in the tomographic image.

10. The anterior ocular segment optical coherence tomographic imaging method according to claim 7 , further comprising a first opacity detection step of determining opacity of the crystalline lens based on the number of edges detected by the layer boundary detection step.

11. The anterior ocular segment optical coherence tomographic imaging method according to claim 7 , further comprising a second opacity detection step of determining opacity of the crystalline lens by determining whether or not a sum and/or an average of the brightness values in the layer detected in the tomographic image is larger than a predetermined threshold.

12. The anterior ocular segment optical coherence tomographic imaging method according to claim 10 , further comprising a second opacity detection step of determining opacity of the crystalline lens by determining whether or not a sum and/or an average of the brightness values in the layer detected in the tomographic image is larger than a predetermined threshold.

Assignees

• Tomey Corp

Inventors

• Okamoto Keiichiro
• Higashita Risa
• Li Fushi
• Kojima Makoto

Classifications

• G06T7/12

  Edge-based segmentation · CPC title

• A61B3/117

  for examining the anterior chamber or the anterior chamber angle, e.g. gonioscopes · CPC title

• G06T2207/10101

  Optical tomography; Optical coherence tomography [OCT] · CPC title

• G06T2207/30041

  Eye; Retina; Ophthalmic · CPC title

• A61B3/1176 Primary

  for determining lens opacity, e.g. cataract · CPC title