Medication delivery device

Patent metadata

Field	Value
Publication number	US-9802003-B2
Application number	US-201314049916-A
Country	US
Kind code	B2
Filing date	Oct 9, 2013
Priority date	May 2, 2008
Publication date	Oct 31, 2017
Grant date	Oct 31, 2017

Abstract

A medication delivery device having a housing having a proximal and a distal end, a medication receptacle designed to be engaged with the distal end of the housing by engagement of a first engagement feature with a second engagement feature and a dosing mechanism. The dosing mechanism includes a piston rod which is rotatable and moveable in a distal direction for medication delivery and a drive device for moving the piston rod in the distal direction for medication delivery. The medication receptacle includes an actuation element that brings a guiding element in a guiding position. The guiding element guides the piston rod for medication delivery. The first engagement feature and the second engagement feature are moveable into engagement by a movement of the medication receptacle which ends in a rotational movement without axial movement of the medication receptacle with respect to the housing.

First claim

What is claimed is:

1. A medication delivery device comprising:
a housing having a proximal end and a distal end,
a medication receptacle designed to be engaged with the distal end of the housing by engagement of a first engagement feature with a second engagement feature and
a dosing mechanism comprising
a piston rod which is moveable in a distal direction for medication delivery and
a drive device for moving the piston rod in the distal direction for medication delivery;
wherein
the medication receptacle comprises an actuation element that brings a guiding element in a guiding position whereby the guiding element guides the piston rod for medication delivery,
wherein the first engagement feature and the second engagement feature are moveable into engagement by a movement of the medication receptacle which ends in a rotational movement without axial movement of the medication receptacle with respect to the housing,
the actuation element thereby bringing the guiding element in the guiding position.

2. The medication delivery device according to claim 1 ,
wherein, in the guiding position, the guiding element is prevented from rotation with respect to the housing.

3. The medication delivery device according to claim 1 ,
wherein, when the guiding element is in the guiding position, the piston rod can be moved axially in the distal direction with respect to the housing.

4. The medication delivery device according to claim 3 ,
wherein the piston rod is prevented from axial movement in the proximal direction with respect to the housing.

5. The medication delivery device according to claim 1 ,
wherein when the guiding element is not in the guiding position, the piston rod is free to move axially in the proximal direction with respect to the housing.

6. The medication delivery device according to claim 1 ,
wherein the first engagement feature and second engagement feature are designed such that for moving the medication receptacle and the housing into engagement, the actuation element is rotated and moved axially with respect to the housing and
are thereafter rotated without being moved axially, thereby bringing the guiding element in the guiding position.

7. The medication delivery device according to claim 1 ,
wherein the guiding element is a nut that is threadedly engaged with the piston rod.

8. The medication delivery device according to claim 1 , wherein
the drive device comprises a drive sleeve and
the piston rod comprises two threaded sections, wherein a first threaded section is provided for threaded engagement with the guiding element and a second threaded section is provided for threaded engagement with the drive sleeve and
wherein a pitch direction of the second threaded section is oppositely directed to a pitch direction of the first threaded section.

9. The medication delivery device according to claim 8 ,
wherein the drive sleeve is engaged with the piston rod for driving the piston rod in the distal direction during medication delivery,
the drive sleeve being moved axially and being prevented from rotation with regard to the housing during medication delivery,
thereby causing axial movement and rotation of the piston rod.

10. The medication delivery device according to claim 9 , wherein the dosing mechanism further comprises:
a dose dial sleeve threadedly engaged to the housing, and
the drive sleeve being releasably coupled to the dose dial sleeve.

11. The medication delivery device according to claim 10 , wherein the dosing mechanism further comprises:
a clutch located between the dose dial sleeve and the drive sleeve,
wherein,
a) when the dose dial sleeve and the drive sleeve are coupled, the clutch allows both to rotate with respect to the housing, and
b) when the dose dial sleeve and the drive sleeve are de-coupled, the clutch allows rotation of the dose dial sleeve with respect to the housing is allowed,
and rotation of the drive sleeve with respect to the housing is prevented and axial movement of the drive sleeve is allowed in the distal direction thereby transferring a force in the distal direction to the piston rod.

12. The medication delivery device according to claim 1 ,
wherein the medication delivery device comprises a lock that is non-rotatable with respect to the housing and that is engageable with the guiding element,
thereby locking the guiding element to prevent rotation of the guiding element with respect to the housing.

13. The medication delivery device according to claim 12 ,
wherein when the guiding element is engaged with the lock in the guiding position, the piston rod is prevented from rotation and axial movement in the proximal direction with respect to the housing but is allowed to rotate and move axially in the distal direction with respect to the housing for medication delivery.

14. The medication delivery device according to claim 13 ,
wherein the guiding element comprises a shape which interacts
with the shape of the actuation element driving the lock and the guiding element into engagement by the rotational movement of the actuation element.

15. The medication delivery device according to claim 13 ,
wherein at least one inclined surface is arranged on the actuation element and at least one correspondingly inclined surface is arranged on the guiding element,
the inclined surfaces being formed such that for interaction of the actuation element and the guiding element, the inclined surfaces glide along each other.

16. The medication delivery device according to claim 15 ,
wherein the actuation element comprises at least one protrusion with the inclined surface fixedly or moveably arranged on the actuation element or at least one ramp with an inclined surface for interacting with the guiding element, thereby driving the guiding element and the lock into engagement.

17. The medication delivery device according to claim 12 ,
wherein the guiding element comprises a nut that is threadedly engaged with the piston rod and
which is engaged with the lock in the guiding position.

18. The medication delivery device according to claim 12 ,
wherein the lock and the guiding element comprise face teeth which interlock when the lock and the guiding element are engaged in the guiding position.

19. The medication delivery device according to claim 12 ,
wherein the lock and the guiding element disengage under the force of a biasing element when the medication receptacle is disengaged from the housing.

20. The medication delivery device according to claim 12 ,
wherein when the medication receptacle is disengaged from the housing, the lock and the guiding element are disengaged,
whereby the guiding element is free to rotate with respect to the housing.

21. The medication delivery device according to claim 1 ,
wherein the medication receptacle comprises a cartridge holder designed to receive a cartridge.

22. The medication delivery device according to claim 1 ,
wherein the medication receptacle comprises the first engagement element and
that the housing comprises the second engagement element.

23. The medication delivery device according to claim 1 ,
wherein the piston rod is rotatable and moveable in the distal direction for medication delivery.

Assignees

• Sanofi Aventis Deutschland

Inventors

• Harms Michael
• Raab Steffen
• Webber Dominic George
• Howarth James Roberts
• Beckett Tevor John
• Gray Geoffrey Philip
• Cross John David

Classifications

• A61M5/31535

  Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose · CPC title

• A61M5/31558

  using scaling up or down transmissions, e.g. gearbox · CPC title

• A61M2205/582

  by tactile feedback · CPC title

• A61M5/31541

  Means preventing setting of a dose beyond the amount remaining in the cartridge · CPC title

• A61M5/31575

  using scaling up or down transmissions, e.g. gearbox · CPC title