Polymer stents and methods of manufacture

Patent metadata

Field	Value
Publication number	US-9801980-B2
Application number	US-201113332048-A
Country	US
Kind code	B2
Filing date	Dec 20, 2011
Priority date	Dec 20, 2010
Publication date	Oct 31, 2017
Grant date	Oct 31, 2017

Abstract

Methods of forming and/or manufacturing polymeric stents are disclosed. Polymeric stents are also disclosed.

First claim

We claim:

1. A method of forming a polymeric stent comprising:
preparing a prepolymer solution comprising a macromer, a monomer and a crosslinker, wherein the macromer includes ethoxylated trimethylol propane triacrylate;
forcing the prepolymer solution onto a textured surface of a first tube wherein the forcing is accomplished by injecting the prepolymer solution into voids created by the textured surface of the first tube and an inner surface of a second tube when the first tube fits inside the second tube and the textured surface of the first tube fits against the inner surface of the second tube;
initiating polymerization of the prepolymer solution to form a polymeric tube on the textured surface; and
modifying the polymeric tube into a desired shape or pattern, wherein the formed polymeric stent has a hydrated radial force of about 1 gf to about 50 gf.

2. The method according to claim 1 wherein the textured surface has a cross-hatched pattern.

3. The method according to claim 1 wherein the first tube substantially fits within the second tube.

4. The method according to claim 1 wherein the modifying comprises laser cutting the polymeric stent to an appropriate length.

5. The method according to claim 1 wherein initiating polymerization of the prepolymer solution is accomplished using heat.

6. The method according to claims 1 wherein initiating polymerization of the prepolymer solution is accomplished using ultraviolet light.

7. The method according to claim 1 wherein the prepolymer solution comprises at least one of alkyl methacrylate, ethylene glycol dimethacrylate, ethoxylated trimethylol propane triacrylate, pentaerythritol triacrylate, di(trimethylol propane) tetraacrylate, hydroxyethyl methacrylate, divinyl benzene, isopropyl alcohol or a combination thereof.

8. A method of forming a polymeric stent comprising:
preparing a prepolymer solution comprising a macromere, a monomer and a cross linker, wherein the macromere includes ethoxylated trimethylol propane triacrylate;
distributing the prepolymer solution onto an outer textured surface of a tube by injecting the prepolymer solution between the outer textured surface and the inner surface of a second tube fit substantially around the outer textured surface wherein the outer textured surface of the tube fits against the inner surface of the second tube;
initiating polymerization of the prepolymer solution using heat;
forming a polymeric stent on the outer textured surface; and
removing the polymeric stent from the tube, wherein the formed polymeric stent has a hydrated radial force of about 1 gf to about 50 gf.

9. A method of forming a polymeric stent comprising:
preparing a prepolymer solution comprising a macromere, a monomer and a cross linker, wherein the macromere includes ethoxylated trimethylol propane triacrylate;
distributing the prepolymer solution onto an inner textured surface of a tube by injecting the prepolymer solution between the inner textured surface and an outer surface of a second tube fit substantially inside the inner textured surface wherein the inner textured surface fits against the outer surface of the second tube;
initiating polymerization of the prepolymer solution using heat;
forming a polymeric stent on the inner textured surface; and
removing the polymeric stent from the tube, wherein the formed polymeric stent has a hydrated radial force of about 1 gf to about 50 gf.

Assignees

• Karino Wataru
• Plotkin Steve
• Cruise Gregory M
• Microvention Inc

Inventors

• Karino Wataru
• Plotkin Steve
• Cruise Gregory M

Classifications

• B29C35/08

  by wave energy or particle radiation {(B29C64/00, B29C71/04 take precedence)} · CPC title

• A61L31/048 Primary

  obtained by reactions only involving carbon-to-carbon unsaturated bonds (A61L31/041 takes precedence) · CPC title

• B29C39/006

  Monomers or prepolymers (by reaction injection moulding B29C67/246) · CPC title

• B29C39/02

  for making articles of definite length, i.e. discrete articles · CPC title

• A61L31/14

  Materials characterised by their function or physical properties {, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials} · CPC title