Compositions for sensitive skin

Patent metadata

Field	Value
Publication number	US-9801900-B2
Application number	US-201414550664-A
Country	US
Kind code	B2
Filing date	Nov 21, 2014
Priority date	Nov 22, 2013
Publication date	Oct 31, 2017
Grant date	Oct 31, 2017

Abstract

Disclosed are compositions and methods for their use that include a combination of hydrolyzed algin, escin, Ruscus aculeatus root extract, ammonium glycyrrhizate, Centella asiatica extract, hydrolyzed yeast protein, and Calendula officinalis flower extract.

First claim

The invention claimed is:

1. A method of reducing CGRP production in skin cells and protecting skin from oxidative damage from free radicals comprising topically applying to skin in need thereof a composition comprising:
butylene glycol;
glycerin;
propylene glycol;
diazolidinyl urea;
PPG-5-ceteth-20;
methylparaben;
sodium citrate;
disodium EDTA;
buteth-3;
propylparaben;
citric acid;
sodium benzotriazolyl butylphenol sulfonate;
panthenol; and
an effective amount of hydrolyzed algin, escin, Ruscus aculeatus root extract, ammonium glycyrrhizate, Centella asiatica extract, hydrolyzed yeast protein, and Calendula officinalis flower extract,

wherein the composition is capable of reducing cytokine production, reducing CGRP production, and protecting skin from oxidative damage from free radicals, and wherein the skin is erythemic, sensitive, inflamed, dry, flaky, and/or itchy skin.

2. The method of claim 1 , wherein the composition further comprises between 80 to 90% by weight of water.

3. The method of claim 2 , wherein the composition comprises 0.005 to 0.05% by weight of hydrolyzed algin.

4. The method of claim 3 , wherein the composition comprises 0.001 to 0.05% by weight of escin, 0.001 to 0.01% by weight of Ruscus aculeatus root extract, 0.001 to 0.01% by weight of ammonium glycyrrhizate, 0.0005 to 0.005% by weight of Centella asiatica extract, 0.0003 to 0.003% by weight of hydrolyzed yeast protein, and 0.0003 to 0.003% by weight of Calendula officinalis flower extract.

5. The method of claim 3 , wherein the composition further comprises Opuntia tuna fruit extract.

6. The method of claim 1 , wherein the composition comprises:
5 to 7% by weight of butylene glycol;
3 to 5% by weight of glycerin;
0.3 to 0.7% by weight of propylene glycol;
0.1 to 0.5% by weight of diazolidinyl urea;
0.1 to 0.5% by weight of PPG-5-ceteth-20;
0.1 to 0.5% by weight of methylparaben;
0.05 to 0.1% by weight of sodium citrate;
0.03 to 0.07% by weight of disodium EDTA;
0.03 to 0.07% by weight of buteth-3;
0.01 to 0.05% by weight of propylparaben;
0.01 to 0.05% by weight of citric acid;
0.01 to 0.05% by weight of sodium benzotriazolyl butylphenol sulfonate; and
0.01 to 0.05% by weight of panthenol.

7. A method of reducing CGRP production in skin cells and protecting skin from oxidative damage from free radicals comprising topically applying to skin in need thereof a composition comprising:
glycerin;
pentylene glycol;
glycereth-26;
propylene glycol;
triethanolamine;
acrylates/C10-30 alkyl acrylate crosspolymer;
diazolidinyl urea;
hydroxyethylcellulose;
sodium polyacrylate;
methylparaben;
disodium EDTA;
butylene glycol;
phenoxyethanol;
caprylyl glycol;
propylparaben;
panthenol; and
an effective amount of hydrolyzed algin, escin, Ruscus aculeatus root extract, ammonium glycyrrhizate, Centella asiatica extract, hydrolyzed yeast protein, and Calendula officinalis flower extract,

wherein the composition is capable of reducing cytokine production, reducing CGRP production, and protecting skin from oxidative damage from free radicals, and wherein the skin is erythemic, sensitive, inflamed, dry, flaky, and/or itchy skin.

8. The method of claim 7 , wherein the composition comprises:
3 to 7% by weight of glycerin;
3 to 7% by weight of pentylene glycol;
1 to 3% by weight of glycereth-26;
0.3 to 0.7% by weight of propylene glycol;
0.3 to 0.7% by weight of triethanolamine;
0.1 to 0.5% by weight of acrylates/C10-30 alkyl acrylate crosspolymer;
0.1 to 0.5% by weight of diazolidinyl urea;
0.1 to 0.5% by weight of hydroxyethylcellulose;
0.1 to 0.5% by weight of sodium polyacrylate;
0.1 to 0.5% by weight of methylparaben;
0.05 to 0.5% by weight of disodium EDTA;
0.05 to 0.1% by weight of butylene glycol;
0.03 to 0.07% by weight of phenoxyethanol;
0.03 to 0.07% by weight of caprylyl glycol;
0.01 to 0.05% by weight of propylparaben; and
0.01 to 0.05% by weight of panthenol.

9. A method of reducing CGRP production in skin cells and protecting skin from oxidative damage from free radicals comprising topically applying to skin in need thereof a composition comprising:
pentylene glycol;
polysilicone-11;
hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer;
dimethicone;
squalane;
glyceryl undecylenate;
silica;
butylene glycol;
triethanolamine;
polysorbate 60;
acrylates/C10-30 alkyl acrylate crosspolymer;
hydroxypropyl cyclodextrin;
sorbitan isostearate;
panthenol;
glycerin; and
an effective amount of hydrolyzed algin, escin, Ruscus aculeatus root extract, ammonium glycyrrhizate, Centella asiatica extract, hydrolyzed yeast protein, and Calendula officinalis flower extract,

wherein the composition is capable of reducing cytokine production, reducing CGRP production, and protecting skin from oxidative damage from free radicals, and wherein the skin is erythemic, sensitive, inflamed, dry, flaky, and/or itchy skin.

10. The method of claim 9 , wherein the composition comprises:
3 to 7% by weight of pentylene glycol;
1 to 5% by weight of polysilicone-11;
1 to 5% by weight of hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer;
1 to 3% by weight of dimethicone;
1 to 3% by weight of squalane;
0.5 to 2% by weight of glyceryl undecylenate;
0.3 to 0.7% by weight of silica;
0.1 to 0.5% by weight of butylene glycol;
0.1 to 0.5% by weight of triethanolamine;
0.1 to 0.5% by weight of polysorbate 60;
0.1 to 0.5% by weight of acrylates/C10-30 alkyl acrylate crosspolymer;
0.05 to 0.1% by weight of hydroxypropyl cyclodextrin;
0.05 to 0.1% by weight of sorbitan isostearate;
0.03 to 0.07% by weight of panthenol; and
0.03 to 0.07% by weight of glycerin.

11. The method of claim 10 , wherein the composition further comprises benzyl alcohol.

12. The method of claim 11 , wherein the composition comprises 0.1 to 1% by weight of benzyl alcohol.

13. A method of reducing CGRP production in skin cells and protecting skin from oxidative damage from free radicals comprising topically applying to skin in need thereof a composition comprising:
glycerin;
pentylene glycol;
glycereth-26;
benzyl alcohol;
triethanolamine;
acrylates/C10-30 alkyl acrylate crosspolymer;
hydroxyethylcellulose;
sodium polyacrylate;
disodium EDTA;
hydroxypropyl cyclodextrin;
butylene glycol;
phenoxyethanol;
caprylyl glycol;
panthenol; and
an effective amount of hydrolyzed algin, escin, Ruscus aculeatus root extract, ammonium glycyrrhizate, Centella asiatica extract, hydrolyzed yeast protein, and Calendula officinalis flower extract,

wherein the composition is capable of reducing cytokine production, reducing CGRP production, and protecting skin from oxidative damage from free radicals, and wherein the skin is erythemic, sensitive, inflamed, dry, flaky, and/or itchy skin.

14. The method of claim 13 , wherein the composition comprises:
3 to 7% by weight of glycerin;
2 to 5% by weight of pentylene glycol;
1 to 3% by weight of glycereth-26;
0.3 to 1.5% by weight of benzyl alcohol;
0.1 to 1.5% by weight of triethanolamine;
0.1 to 0.7% by weight of acrylates/C10-30 alkyl acrylate crosspolymer;
0.01 to 1.0% by weight of hydroxyethylcellulose;
0.01 to 1.0% by weight of sodium polyacrylate;
0.01 to 1.0% by weight of disodium EDTA;
0.01 to 1.0% by weight of hydroxypropyl cyclodextrin;
0.01 to 1.0% by weight of butylene glycol;
0.01 to 1.0% by weight of phenoxyethanol;
0.01 to 0.1% by weight of caprylyl glycol; and
0.005 to 0.1% by weight of panthenol.

Assignees

• Mary Kay Inc

Inventors

• Gan David
• Florence Tiffany
• Hines Michelle
• Sanchez Milagros
• Jacoby Patricia
• Hart Linda

Classifications

• A61K8/9789

  Magnoliopsida [dicotyledons] · CPC title

• A61K31/704

  attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin {(digitoxin A61K31/7048)} · CPC title

• A61K38/011

  from plants · CPC title

• A61K38/16

  Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof {(enzyme inhibitors A61K38/005)} · CPC title

• A61Q19/005

  Preparations for sensitive skin · CPC title