Methods of delivering a health care active by administering personal health care articles comprising a filmament

Patent metadata

Field	Value
Publication number	US-9801830-B2
Application number	US-201313893373-A
Country	US
Kind code	B2
Filing date	May 14, 2013
Priority date	Jul 2, 2010
Publication date	Oct 31, 2017
Grant date	Oct 31, 2017

Abstract

A method of delivering a health care active having the steps of administering to a mammal in need of a health benefit or a treatment for a health condition a personal health care article and consuming the article. The article contains one or more filaments that contain a backbone material, a health care active and optionally aesthetic agents, extensional aids, plasticizers, and crosslinking agents.

First claim

What is claimed is:

1. A personal health care article comprising a nonwoven web comprising a plurality of interwoven filaments, the filaments comprise:
a. from about 10% to about 80%, by weight on a dry filament basis, of one or more backbone materials;
b. greater than 50%, by weight on a dry filament basis, of one or more health care actives wherein said health care actives are releasable from said filaments wherein said filaments are exposed to conditions of intended use;
c. less than 10%, by weight of the filament, moisture; and
d. an aesthetic agent selected from the group consisting of flavors, sensates, sweeteners, salivation agents, and combinations thereof;
wherein at least one of the filaments exhibits a length of greater than 5.08 cm;
wherein the article is administrable via the oral cavity and swallowable;
and wherein the nonwoven web comprises greater than 50% by weight of the one or more health care actives.

2. The article of claim 1 , wherein the filaments are present in the nonwoven web at a basis weight of from about 20 g/m 2 to about 1000 g/m 2 .

3. The article of claim 1 , wherein said filament is a meltblown filament.

4. The article of claim 1 , wherein said backbone material is selected from the group consisting of polymers, sugars, and combinations thereof.

5. The article of claim 1 , wherein said one or more backbone materials are a polymer.

6. The article of claim 5 , wherein said polymer is polyvinyl alcohol, pullulan, pectin, corn starch, modified corn starch, or hydroxypropyl methylcellulose.

7. The article of claim 5 , wherein said polymer is selected from the group consisting of naturally sourced polymers, synthetic polymers, and combinations thereof.

8. The article of claim 5 , wherein said naturally sourced polymer is selected from the group consisting of alginates, starch based polymers, native starches, modified starches, and combinations thereof.

9. The article of claim 5 , wherein said polymer exhibits a weight average molecular weight of from about 20,000 Da to about 200,000 Da.

10. The article of claim 5 , wherein said polymer exhibits a weight average molecular weight of from about 1,000,000 Da to about 6,000,000 Da.

11. The article of claim 1 , further comprising a filament-forming material selected from the group consisting of extensional aids, plasticizers, crosslinking agents, and combinations thereof.

12. The article of claim 1 , wherein said filaments comprise two or more different backbone materials.

13. The article of claim 1 , wherein said one or more health care actives are selected from the group consisting of respiratory agents, gastrointestinal agents, central nervous system agents, anti-infective agents, nutritional agents, overall wellbeing agents, and combinations thereof.

14. The article of claim 1 , wherein said filaments comprise two or more different health care actives.

15. A personal health care article comprising a nonwoven web comprising a plurality of interwoven filaments, the filaments comprise:
a. from about 10% to about 80%, by weight on a dry filament basis, of one or more backbone materials;
b. greater than 50%, by weight on a dry filament basis, of one or more health care actives wherein said health care actives are releasable from said filaments wherein said filaments are exposed to conditions of intended use wherein the health care actives are selected from the group consisting of respiratory agents, gastrointestinal agents, nutritional agents, and combinations thereof;
c. less than 10%, by weight of the filament, moisture; and
d. an aesthetic agent selected from the group consisting of flavors, sensates, sweeteners, salivation agents, and combinations thereof;
wherein at least one of the filaments exhibits a length of greater than 5.08 cm;
wherein the article is administrable via the oral cavity and swallowable; wherein the filaments exhibit a diameter of greater than 1 μm as measured according to the Diameter Test Method; and
wherein the nonwoven web comprises greater than 50% by weight of the one or more health care actives.

16. The article of claim 1 , wherein the one or more health care actives are selected from the group consisting of naproxen, doxylamine succinate, dextromethorphan, and combinations thereof.

17. The article of claim 1 , wherein the one or more health care actives comprise diphenhydramine.

Assignees

• Procter & Gamble

Inventors

• Darcy Trevor John
• Gilbert Steven Ray
• Gordon Gregory Charles
• Chhabra Rajeev
• Allen Jr William Maxwell

Classifications

• A61P31/00

  Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics · CPC title

• A61P3/02

  Nutrients, e.g. vitamins, minerals · CPC title

• A61P25/28

  for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia · CPC title

• A61P11/00

  Drugs for disorders of the respiratory system · CPC title

• A61P1/00

  Drugs for disorders of the alimentary tract or the digestive system · CPC title