Analyte sensors and sensing methods featuring low-potential detection
US-2024402120-A1 · Dec 5, 2024 · US
US9801574B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9801574-B2 |
| Application number | US-201514875539-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 5, 2015 |
| Priority date | May 22, 2002 |
| Publication date | Oct 31, 2017 |
| Grant date | Oct 31, 2017 |
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The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observable using photomicroscopy at 400× magnification or less. In one aspect, the homogeneous membrane of the present invention has hydrophilic domains dispersed substantially throughout a hydrophobic matrix to provide an optimum balance between oxygen and glucose transport to an electrochemical glucose sensor.
Opening claim text (preview).
What is claimed is: 1. An implantable device for measuring an analyte in a biological fluid, comprising: an implantable sensor comprising an electrochemically reactive surface; and a membrane disposed over at least a portion of the electrochemically reactive surface, wherein the membrane comprises a matrix comprising a first polymer and a second polymer dispersed throughout the matrix, wherein the first polymer is polyurethane urea, wherein the second polymer comprises at least…
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