Chromophoric polymer dots
US-2016341737-A1 · Nov 24, 2016 · US
Highly fluorescent polymer nanoparticle
US9797840B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9797840-B2 |
| Application number | US-201213687813-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 28, 2012 |
| Priority date | Nov 28, 2011 |
| Publication date | Oct 24, 2017 |
| Grant date | Oct 24, 2017 |
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- Title
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- Abstract
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Abstract
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Fluorescent nanoparticles are provided. The nanoparticles are formed from poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-(1-cyanovinylene-1,4-phenylene)]. Also provided are methods for imaging a target to which the nanoparticles are bound.
First claim
Opening claim text (preview).
The embodiments of the invention in which an exclusive property or privilege is claimed are defined as follows: 1. A nanoparticle consisting essentially of: poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-(1-cyanovinylene-1,4-phenylene)]; a copolymer; and a binding moiety covalently attached to the copolymer, wherein the binding moiety is a protein, and wherein the nanoparticle has a hydrodynamic diameter of 1-30 nm and a quantum yield of about 60%. 2. The nanoparticle of claim 1 , wherein the hydrodynamic diameter is 20 nm or less. 3. The nanoparticle of claim 1 , having a fluorescence emission peak in the range of about 590 nm to about 620 nm. 4. The nanoparticle of claim 1 , wherein the nanoparticle is formed using nanoprecipitation. 5. The nanoparticle of claim 1 , wherein the copolymer is poly(styrene-co-maleic anhydride). 6. The nanoparticle of claim 1 , wherein the binding moiety is positioned at the surface of the nanoparticle.
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Classifications
Particulate matter [e.g., sphere, flake, etc.] · CPC title
- G01N33/588Primary
with semiconductor nanocrystal label, e.g. quantum dots · CPC title
Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors · CPC title
- G01N21/6486Primary
Measuring fluorescence of biological material, e.g. DNA, RNA, cells (G01N21/6428 takes precedence) · CPC title
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Frequently asked questions
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- What does patent US9797840B2 cover?
- Fluorescent nanoparticles are provided. The nanoparticles are formed from poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-(1-cyanovinylene-1,4-phenylene)]. Also provided are methods for imaging a target to which the nanoparticles are bound.
- Who is the assignee on this patent?
- Univ Washington Through Its Center For Commercialization
- What technology area does this patent fall under?
- Primary CPC classification G01N33/588. Mapped technology areas include Physics.
- When was this patent published?
- Publication date Tue Oct 24 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 5 related publications on this page (citations in our corpus or others sharing the same primary CPC).