Pumping systems for cassette-based dialysis

Patent metadata

Field	Value
Publication number	US-9795729-B2
Application number	US-201414283382-A
Country	US
Kind code	B2
Filing date	May 21, 2014
Priority date	Jul 19, 2002
Publication date	Oct 24, 2017
Grant date	Oct 24, 2017

Abstract

A dialysis machine includes: a hardware unit including at least one pump actuator, at least one valve actuator and a cassette interface, the cassette interface including: (i) a plate that abuts the cassette; (ii) at least one pump aperture defined by the plate; (iii) at least one pump head moveable out of and retractable into the at least one pump aperture to operate a pumping portion of the cassette; (iv) at least one valve aperture defined by the plate; (v) at least one valve apparatus moveable out of and retractable into the at least one valve aperture to operate a valve portion of the cassette; (vi) at least one sensor aperture defined by the plate; and (vii) at least one sensor located in the least one sensor aperture, the at least one sensor operable with a sensor portion of the cassette.

First claim

The invention is claimed as follows:

1. A peritoneal dialysis method comprising:
enabling a disposable pumping cassette to be aligned so that (i) a soft side of the disposable pumping cassette faces towards a vacuum chamber and a rigid piston head of a peritoneal dialysis machine, the rigid piston head attached to a rigid piston shaft that is connected mechanically to a stepper motor via a coupler, and (ii) a dialysis fluid supply line, a patient line and a drain line extend from a hard part of the disposable cassette to the outside of the peritoneal dialysis machine and communicate with a respective dialysis fluid supply container, a patient and a drain;
positioning the rigid piston head relative to the vacuum chamber such that the rigid piston shaft translates back and forth within the vacuum chamber;
applying a vacuum from a negative pressure source communicating pneumatically through the vacuum chamber such that the soft side of the disposable pumping cassette is pulled into contact with a surface of the rigid piston head to at least partially mate the soft side of the disposable pumping cassette with the rigid piston head;
operating a stepper motor such that the rigid piston head and the soft side of the disposable pumping cassette extend at least partially into the hard part of the disposable pumping cassette so as to push (i) fresh dialysis fluid from the disposable pumping cassette, through the patient line or (ii) used dialysis fluid from the disposable cassette, through the drain line and to the drain; and
operating the stepper motor such that the rigid piston head retracts from the hard part of the disposable pumping cassette while the negative pressure source applies a vacuum through the vacuum chamber to the soft side of the disposable pumping cassette to hold the soft side in at least partial contact with the surface of the rigid piston head so as to draw (i) fresh dialysis fluid from the dialysis fluid supply container through the supply line and into the disposable pumping cassette through the supply line or (ii) used dialysis fluid from the patient through the patient line and into the disposable pumping cassette.

2. The peritoneal dialysis method of claim 1 , which includes retracting the rigid piston head completely out of the hard part of the disposable pumping cassette and alternating the soft side of the disposable pumping cassette to move away from the hard side of the disposable pumping cassette.

3. The peritoneal dialysis method of claim 1 , which includes extending the rigid piston head at least partially into the hard part of the disposable pumping cassette by a preset distance using the stepper motor.

4. The peritoneal dialysis method of claim 1 , which includes enabling the disposable pumping cassette to be aligned with the peritoneal dialysis machine at a non-vertical angle.

5. The peritoneal dialysis method of claim 1 , which includes conforming the shape and size of the rigid piston head to a shape and size of a pump chamber portion of the hard part of the disposable cassette.

6. The peritoneal dialysis method of claim 1 , which includes positioning the rigid piston head relative to the vacuum chamber such that the rigid piston shaft moves back and forth sealingly within the vacuum chamber.

7. The peritoneal dialysis method of claim 1 , which includes configuring the disposable cassette so that when accepted by the peritoneal dialysis machine multiple dialysis fluid supply lines extend from a same surface of the peritoneal dialysis machine.

8. A peritoneal dialysis method comprising:
enabling the mating of a disposable pumping cassette with a peritoneal dialysis machine having first and second rigid piston heads attached to first and second respective rigid piston shafts;
operating a stepper motor such that the first and second rigid piston shafts are moved within a vacuum chamber towards the disposable pumping cassette and the first and second respective rigid piston heads contact and move first and second respective portions of a flexible membrane of the disposable pumping cassette into a rigid portion of the disposable pumping cassette to push (i) fresh dialysate out of the disposable pumping cassette, through a patient line towards a patient or (ii) used dialysate out of the disposable pumping cassette, through a drain line towards a drain; and
using a negative pressure source communicating pneumatically through the vacuum chamber to apply (a) a first vacuum mating the first portion of the flexible membrane to a surface of the first rigid piston head and (b) a second vacuum mating the second portion of the flexible membrane to a surface of the second rigid piston head, causing the first and second portions of the flexible membrane to respectively follow the first and second rigid piston heads as either rigid piston head is moved away from the disposable pumping cassette to pull (i) fresh dialysate from a fresh dialysate supply line into the disposable pumping cassette or (ii) used dialysate from the patient line to fill a respective first or second pump chamber of the disposable pumping cassette.

9. The peritoneal dialysis method of claim 8 , which in a first stroke includes moving the first rigid piston head towards the disposable pumping cassette to push fresh dialysate through the patient line or used dialysate through the drain line while moving the second rigid piston head away from the disposable pumping cassette to pull fresh dialysate from the dialysate supply line or used dialysate from the patient line, respectively.

10. The peritoneal dialysis method of claim 9 , which in a second stroke includes moving the first rigid piston head away from the disposable pumping cassette to pull fresh dialysate from the dialysate supply line or used dialysate from the patient line, while moving the second rigid piston head towards the disposable pumping cassette to push fresh dialysate through the patient line or used dialysate through the drain line, respectively.

11. The peritoneal dialysis method of claim 8 , which includes prompting a fluid connection of the patient line to an indwelling patient catheter after mating the disposable pumping cassette to the peritoneal dialysis machine.

12. The peritoneal dialysis method of claim 11 , which includes moving the first and second rigid piston heads and applying the first and second vacuums to prime the disposable pumping cassette with fresh dialysate prior to prompting the fluid connection.

13. A peritoneal dialysis method comprising:
applying a vacuum to a pumping portion of a flexible membrane of a dialysis fluid carrying pumping cassette aligned with a vacuum chamber, the vacuum generated from a negative pressure source communicating pneumatically with the vacuum chamber;
turning a stepper motor shaft a controlled amount to move a rigid piston shaft and a rigid piston head attached to the rigid piston shaft such that the rigid piston head contacts and moves the pumping portion of the flexible membrane into the dialysis fluid carrying pumping cassette, thereby causing (i) fresh dialysis fluid to be pushed out of the dialysis fluid carrying pumping cassette, through a patient line connected to a patient connector or (ii) used dialysis fluid to be pumped out of the dialysis fluid carrying pumping cassette, through a drain line connected to a drain; and
turning the stepper motor shaft in an opposite direction a controlled amount to move the rigid piston shaft and the rigid piston head such that the rigid piston head retracts within the pumping portion of the flexible membrane of the dialysis fluid carrying pumping cassette, the vacuum generated from the negative pressure source causing the

Assignees

• Baxter Int
• Baxter Healthcare Sa
• Baxter Healthcare Sa

Inventors

• Childers Robert W
• Lauman Brian

Classifications

• A61M2205/122

  using evacuated interfaces to enhance contact · CPC title

• A61M1/28

  Peritoneal dialysis {; Other peritoneal treatment, e.g. oxygenation} · CPC title

• A61M1/16

  with membranes · CPC title

• A61M1/284

  Continuous flow peritoneal dialysis [CFPD] · CPC title

• A61M1/1696 Primary

  with dialysate regeneration · CPC title