Medical devices for mapping cardiac tissue

Patent metadata

Field	Value
Publication number	US-9795314-B2
Application number	US-201615231709-A
Country	US
Kind code	B2
Filing date	Aug 8, 2016
Priority date	May 9, 2014
Publication date	Oct 24, 2017
Grant date	Oct 24, 2017

Abstract

Medical devices and methods for making and using medical devices are disclosed. An example method may include a method of identifying an activation time in a cardiac electrical signal. The method may include sensing a cardiac electrical signal, generating an approximation signal based at least in part on one or more parameters of the cardiac electrical signal, identifying a fiducial point on the approximation signal and determining, based at least in part on a timing of the fiducial point in the approximation signal, an activation time in the cardiac electrical signal.

First claim

What is claimed is:

1. A system for mapping the electrical activity of the heart, the system comprising:
a catheter comprising a plurality of electrodes positioned on a distal end of the catheter, the plurality of electrodes configured to sense a plurality of signals, wherein each of the plurality of signals is a function of time;
a processor configured to:
receive the plurality of signals sensed by the plurality of electrodes;
generate a plurality of alternate signals, wherein each alternate signal is a function of frequency and wherein each alternate signal of the plurality of alternate signals corresponds to a respective signal of the plurality signals;
generate a composite signal of the plurality of alternate signals;
determine a characteristic frequency from the generated composite signal by identifying a frequency of the composite signal having a maximum power; and
outputting to a display device the determined characteristic frequency.

2. The system of claim 1 , wherein to generate a composite signal of the plurality of signals, the processor is configured to calculate: a mean, a median or a mode at each frequency of the plurality of alternate signals.

3. The system of claim 1 , wherein the processor is configured to:
determine a plurality of phase values that correlates each alternate signal to its respective signal of the plurality of signals;
phase shift each of the plurality of alternate signals using a respective phase value of the plurality of phase values; and
generate the composite signal using the phase shifted alternate signals.

4. The system of claim 1 , wherein the processor is configured to determine at least one fiducial of the composite signal.

5. The system of claim 4 , wherein to determine at least one fiducial, the processor is configured to determine at least one of: a peak amplitude, change in slope and deflection of the correlated sinusoidal signal.

6. The system of claim 4 , wherein to determine at least one fiducial, the processor is configured to determine a window for the composite signal and determine the at least one fiducial within the determined window.

7. The system of claim 4 , wherein the at least one fiducial corresponds to an activation time.

8. The system of claim 1 , further comprising a band-pass filter configured to filter the sensed signals of the plurality of signals.

9. The system of claim 8 , wherein the band-pass filter filters signals outside of the 3 to 7 Hz band.

10. The system of claim 1 , wherein to generate a plurality of alternate signals, the processor is configured to: transform the sensed plurality of signals using a Fourier Transform or a Fast Fourier Transform, Wavelet Transform or Wigner-Ville Transform.

11. A method for mapping the electrical activity of the heart, the method comprising:
receiving a plurality of signals sensed by a plurality of electrodes positioned within the heart, wherein each of the plurality of signals is a function of time;
generating a plurality of sinusoidal signals, wherein each sinusoidal signal of the plurality of sinusoidal signals corresponds to a respective signal of the plurality of signals;
determining a plurality of phase values that correlates each sinusoidal signal to its respective signal of the plurality of signals;
phase shifting each sinusoidal signal using a respective phase value of the plurality of phase values; and
generating a composite signal using the phase-shifted sinusoidal signals; and
outputting the generated composite signal to a display device.

12. The method of claim 11 , further comprising characterizing each sinusoidal signal in an analytic representation.

13. The method of claim 12 , wherein characterizing each sinusoidal signal in an analytic representation comprises applying a Hilbert transform to each sinusoidal signal.

14. The method of claim 11 , further comprising determining at least one fiducial of the generated composite signal.

15. The method of claim 14 , wherein determining at least one fiducial comprises determining a window for the composite signal and determining the at least one fiducial within the determined window.

16. The method of claim 14 , wherein the at least one fiducial corresponds to an activation time.

17. The method of claim 14 , wherein determining at least one fiducial comprises determining at least one of: a peak amplitude, change in slope and deflection of the correlated sinusoidal signal.

18. A method for mapping the electrical activity of the heart, the method comprising:
receiving a plurality of signals sensed by a plurality of electrodes positioned within a heart;
generating a plurality of alternate signals, wherein each alternate signal is a function of frequency and wherein each alternate signal of the plurality of alternate signals corresponds to a respective signal of the plurality of signals;
generating a composite signal of the plurality of alternate signals by calculating, at each frequency of the plurality of alternate signals, at least one of: a mean, a median, and a mode; and
outputting to a display device the generated composite signal.

19. The method of claim 18 , wherein generating the plurality of alternate signals comprises transforming the plurality of signals using a Fourier Transform or a Fast Fourier Transform, Wavelet Transform or Wigner-Ville Transform.

20. The method of claim 18 , further comprising:
characterizing each alternate signal of the plurality of alternate signals in an analytic representation;
generating a composite signal using the analytic representations of the alternate signals; and
outputting to a display device the generate composite signal using the representations of the alternate signals.

Assignees

• Boston Scient Scimed Inc
• Boston Scient Scimed Inc

Inventors

• Laughner Jacob I
• Hultz Paul
• Shome Shibaji
• Thakur Pramodsingh H
• Meyer Scott A

Classifications

• A61B5/339

  Displays specially adapted therefor · CPC title

• A61B5/367 Primary

  Electrophysiological study [EPS], e.g. electrical activation mapping or electro-anatomical mapping · CPC title

• A61B5/04525

  Human Necessities · mapped topic

• A61B5/04012

  Human Necessities · mapped topic

• A61B5/04014 Primary

  Human Necessities · mapped topic