Systems and methods for gas pre-separation for detection of substances

Patent metadata

Field	Value
Publication number	US-9789434-B1
Application number	US-201615082108-A
Country	US
Kind code	B1
Filing date	Mar 28, 2016
Priority date	Mar 28, 2016
Publication date	Oct 17, 2017
Grant date	Oct 17, 2017

Abstract

The present disclosure is directed to methods and systems for detecting a substance in a sample gas. The methods and systems include separating the substance of interest in the sample gas, and introducing the separated sample gas into a detector. The systems and methods further include performing an analysis of the substance of interest.

First claim

What is claimed is:

1. A system for detecting a substance of interest, the system comprising:
a sample inlet, configured to receive a sample including at least one substance of interest;
an analysis device including a multi-capillary column (MCC) separation device located therein, the MCC separation device coupled in flow communication with the sample inlet and configured to separate the at least one substance of interest, wherein the MCC separation device is configured to transfer the at least one separated substance of interest into the analysis device for analysis at a flow rate of from about 10 ml/min to about 500 ml/min; and wherein the analysis device is configured to perform an analysis of the at least one separated substance of interest transferred from the MCC separation device; and
a purge line in flow communication with the MCC separation device configured to purge contaminants therefrom.

2. The system of claim 1 , wherein the MCC separation device is configured to transfer the at least one substance of interest into the analysis device at a flow rate of from about 50 ml/min to about 200 ml/min.

3. The system of claim 1 , wherein the MCC separation device is further configured to temporally separate the at least one substance of interest.

4. The system of claim 3 , wherein the sample includes more than one substance of interest.

5. The system of claim 4 , wherein the MCC separation device is configured to transfer the substances of interest into the analysis device at different times.

6. The system of claim 1 , wherein the at least one substance of interest includes at least one of nitro, nitrate, triacetone triperoxide (TATP), ammonium nitrate (AN), ammonium nitrate fuel oil (ANFO), urea nitrate (UN), 2,4,6-trinitrophenylmethylnitramine (tetryl), trinitrotoluene (TNT), ethylene glycol dinitrate (EGDN), nitroglycerin (NG), pentaerythritol tetranitrate (PETN), high melting explosive (HMX), Research Department Explosive (RDX), black powder, cocaine, 3,4-methylenedioxy-N-methylamphetamine (MDMA), an opiate, diazepam and combinations thereof.

7. The system of claim 1 , wherein the analysis device includes at least one of an ion mobility spectrometer (IMS), an ion trap mobility spectrometer (ITMS), a drift spectrometer (DS), a non-linear drift spectrometer, a field ion spectrometer (FIS), a radio frequency ion mobility increment spectrometer (IMIS), a field asymmetric ion mobility spectrometer (FAIMS), an ultra-high-field FAIMS, a differential ion mobility spectrometer (DIMS) and a differential mobility spectrometer (DMS), a traveling wave ion mobility spectrometer, a semiconductor gas sensor, a raman spectrometer, a laser diode detector, a mass spectrometer (MS), an electron capture detector, a photoionization detector, a chemiluminescence-based detector, an electrochemical sensor, an infrared spectrometer, a lab-on-a-chip detector and combinations thereof.

8. The system of claim 1 , further comprising at least one of a heating element and a cooling element in thermal communication with the MCC separation device.

9. The system of claim 8 , wherein the MCC separation device is heated to a temperature of between about 20° C. to about 300° C.

10. A method for detecting a substance of interest, the method comprising:
separating at least one substance of interest from a sample, wherein the at least one substance of interest is separated in a multi-capillary column (MCC);
separating at least one contaminant from the sample, wherein the at least one contaminant is separated in the MCC;
transferring the at least one contaminant from the MCC into a purge line; and
transferring the at least one separated substance of interest from the MCC into a detector, wherein the at least one separated substance of interest is transferred into the detector at a flow rate of from about 10 ml/min to about 500 ml/min, wherein the detector performs an analysis of the at least one separated substance of interest and detects the at least one substance of interest.

11. The method of claim 10 , wherein the MCC is configured to transfer the at least one substance of interest into the detector at a flow rate of from about 50 ml/min to about 200 ml/min.

12. The method of claim 10 , wherein the MCC is further configured to temporally separate the at least one substance of interest.

13. The method of claim 12 , wherein the sample includes more than one substance of interest.

14. The method of claim 13 , wherein the MCC is configured to transfer the substances of interest into the detector at different times.

15. The method of claim 10 , wherein the at least one substance of interest includes at least one of nitro, nitrate, triacetone triperoxide (TATP), ammonium nitrate (AN), ammonium nitrate fuel oil (ANFO), urea nitrate (UN), 2,4,6-trinitrophenylmethylnitramine (tetryl), trinitrotoluene (TNT), ethylene glycol dinitrate (EGDN), nitroglycerin (NG), pentaerythritol tetranitrate (PETN), high melting explosive (HMX), Research Department Explosive (RDX), black powder, cocaine, 3,4-methylenedioxy-N-methylamphetamine (MDMA), an opiate, diazepam and combinations thereof.

16. The method of claim 10 , wherein the detector includes at least one of an ion mobility spectrometer (IMS), an ion trap mobility spectrometer (ITMS), a drift spectrometer (DS), a non-linear drift spectrometer, a field ion spectrometer (FIS), a radio frequency ion mobility increment spectrometer (IMIS), a field asymmetric ion mobility spectrometer (FAIMS), an ultra-high-field FAIMS, a differential ion mobility spectrometer (DIMS) and a differential mobility spectrometer (DMS), a traveling wave ion mobility spectrometer, a semiconductor gas sensor, a raman spectrometer, a laser diode detector, a mass spectrometer (MS), an electron capture detector, a photoionization detector, a chemiluminescence-based detector, an electrochemical sensor, an infrared spectrometer, a lab-on-a-chip detector and combinations thereof.

17. The method of claim 10 , further comprising at least one of a heating element and a cooling element in thermal communication with the MCC.

18. The method of claim 17 , wherein the MCC is heated to a temperature of between about 20° C. to about 300° C.

19. The method of claim 10 , wherein into the detector is located within the detector.

Assignees

• Morpho Detection Llc

Inventors

• Lai Hanh T
• Mishra Vibha
• Platow Wilhelm P

Classifications

• G01N1/2214

  by sorption · CPC title

• Y10T436/25375

  Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] · CPC title

• G01N1/2273

  Atmospheric sampling · CPC title

• B01D53/025 Primary

  with wetted adsorbents; Chromatography (analytical chromatography G01N30/00 - G01N30/96; for liquids B01D15/08) · CPC title

• G01N1/2202

  involving separation of sample components during sampling · CPC title