Colon-targeted active agent delivery carrier and uses thereof
US-2024390501-A1 · Nov 28, 2024 · US
Process for producing oral dosage forms with controlled release
US9789065B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9789065-B2 |
| Application number | US-200913122827-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 2, 2009 |
| Priority date | Oct 7, 2008 |
| Publication date | Oct 17, 2017 |
| Grant date | Oct 17, 2017 |
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- Title
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Abstract
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A process for producing solid oral dosage forms with controlled active ingredient release, comprising a mixture of a) at least one active ingredient, and b) a preformulated mixture of polyvinyl acetate and polyvinylpyrrolidone, wherein the mixture is obtained by joint processing of components a) and b) in an extruder at temperatures between 50° and 200° C.
First claim
Opening claim text (preview).
We claim: 1. A process for producing solid oral dosage forms with controlled active ingredient release, comprising a mixture of: a) at least one active ingredient, and b) a preformulated mixture of polyvinyl acetate and polyvinylpyrrolidone; wherein the mixture is obtained by joint processing of components a) and b) in an extruder at temperatures between 80° and 180° C.; wherein said preformulated mixture is obtained by dissolving polyvinylpyrrolidone in a fine-particle aqueous dispersion of polyvinyl acetate with a particle size of the polyvinyl acetate particles of from 100 to 300 nm, and subsequently spray driving; and wherein extrusion takes place under a pressure of from 2 to 25 MPa; wherein a film with a layer thickness of 100-1000 μm is extruded, from which small pieces of film for oral administration are cut out directly thereafter.
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obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates · CPC title
obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates · CPC title
- A61K9/1694Primary
resulting in granules or microspheres of the matrix type containing more than 5% of excipient · CPC title
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- What does patent US9789065B2 cover?
- A process for producing solid oral dosage forms with controlled active ingredient release, comprising a mixture of a) at least one active ingredient, and b) a preformulated mixture of polyvinyl acetate and polyvinylpyrrolidone, wherein the mixture is obtained by joint processing of components a) and b) in an extruder at temperatures between 50° and 200° C.
- Who is the assignee on this patent?
- Kolter Karl, Maschke Angelika, Basf Se
- What technology area does this patent fall under?
- Primary CPC classification A61K9/1694. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Oct 17 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).