Oral care compositions and methods

Patent metadata

Field	Value
Publication number	US-9789048-B2
Application number	US-201315106507-A
Country	US
Kind code	B2
Filing date	Dec 20, 2013
Priority date	Dec 20, 2013
Publication date	Oct 17, 2017
Grant date	Oct 17, 2017

Abstract

Provided is an oral care composition comprising a phosphate/acrylate co-polymer, a tin salt, and an orally acceptable carrier, and methods of using the same.

First claim

What is claimed is:

1. An oral care composition comprising a phosphate/acrylate co-polymer, a tin salt, and an orally acceptable carrier, wherein the phosphate/acrylate co-polymer is a co-polymerized product of a mixture of acrylic acid, methacrylic acid, and a mixture of 2-hydroxyethyl methacrylate phosphates of Formula 1:

wherein n is 0, 1 or 2.

2. The composition of claim 1 , wherein the phosphate/acrylate co-polymer is a co-polymerized product of a mixture of acrylic acid, methacrylic acid, and 2-hydroxyethyl methacrylate phosphates of Formula 1 comprising acrylic acid in a molar percentage of 70-90%; methacrylic acid in a molar percentage of 5-20%, and hydroxyethyl methacrylate phosphates of Formula 1 in a molar percentage of 1-10%.

3. The composition of claim 1 , wherein the phosphate/acrylate co-polymer is a co-polymerized product of a mixture of acrylic acid, methacrylic acid, and 2-hydroxyethyl methacrylate phosphates of Formula 1 comprising acrylic acid in a molar percentage of 80-90% or 85%; methacrylic acid in a molar percentage of 5-15% or 11%, and hydroxyethyl methacrylate phosphates of Formula 1 in a molar percentage of 2-6% or 4%.

4. The composition of claim 1 , wherein the phosphate/acrylate copolymer is a random copolymer having a weight average molecular weight of 10,000 to 500,000, and the phosphate/acrylate copolymer is below its glass transition temperature.

5. The composition of claim 4 , wherein the weight average molecular weight is 10,000 to 200,000 grams per mole, optionally, 10,000 to 40,000, 15,000 to 25,000, or 17,000 to 23,000 grams per mole.

6. The composition of claim 1 wherein the tin salt is selected from stannous chloride, stannous fluoride and mixtures thereof.

7. The composition of claim 1 , wherein the tin salt comprises SnCl 2 .

8. The composition of claim 1 , wherein the composition comprises 0.1 to 10 weight % SnCl 2 , optionally 0.1 to 5 weight %, 0.1 to 3 weight %, 0.1 to 1.5 weight %, or 0.5 to 1.2 weight % SnCl 2 .

9. The composition of claim 1 , wherein the composition comprises one or more of water, a thickener, a buffer, a humectant, a surfactant, an abrasive, a sweetener, a flavorant, a pigment, a dye, an anti-caries agent, an anti-bacterial, a whitening agent, a desensitizing agent, a vitamin, a preservative, an enzyme, or a mixture thereof.

10. The composition of claim 9 , wherein the anti-bacterial agent is selected from the group consisting of triclosan, cetylpyridinium chloride (CPC), chlorhexidine (CHX), water soluble zinc salts, water insoluble zinc salts, zinc oxide, zinc citrate, or a mixture thereof.

11. The composition of claim 1 , wherein the composition is a mouthwash, toothpaste, tooth gel, tooth powder, non-abrasive gel, mousse, foam, mouth spray, lozenge, oral tablet, dental implement, or pet care product.

12. A method for the treatment and/or inhibition of a chemical stain, plaque, acid erosion, and/or tartar on a dental surface, comprising contacting the dental surface with a composition of claim 1 .

13. A method for the treatment and/or inhibition of gum disease comprising contacting the oral cavity with a composition of claim 1 .

14. A method for the treatment and/or inhibition of halitosis comprising contacting the oral cavity with a composition of claim 1 .

15. A method for the inhibition of biofilm formation on a dental surface comprising contacting the oral cavity with a composition of claim 1 .

16. A method for treating and/or inhibiting bacteria from sticking together and growing into bigger colonies in an oral cavity comprising contacting the oral cavity with a composition of claim 1 .

Assignees

• Colgate Palmolive Co

Inventors

• Prencipe Michael
• Jogun Suzanne
• Won Betty

Classifications

• A61P31/04

  Antibacterial agents · CPC title

• A61P1/02

  Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis · CPC title

• C09D143/02

  Homopolymers or copolymers of monomers containing phosphorus · CPC title

• A61K8/43

  Guanidines · CPC title

• A61K8/347

  Phenols · CPC title