Method for treating at least one biological sample containing a target microorganism

Patent metadata

Field	Value
Publication number	US-9784654-B2
Application number	US-201314441492-A
Country	US
Kind code	B2
Filing date	Nov 7, 2013
Priority date	Nov 7, 2012
Publication date	Oct 10, 2017
Grant date	Oct 10, 2017

Abstract

One embodiment provides a device for processing at least one biological sample capable of containing at least one target microorganism within at least one container. The device having at least one displacement device for generating the displacement of the contents of the at least one container and at least one site for receiving the at least one container. Additionally, the at least one container can receive the at least one biological sample within the at least one container, the container being delimited by a wall fixed on a base. Further, the at least one displacement device may be movable with respect to the base, and the at least one container may include a flexible material which allows the at least one container to be compressed against said wall.

First claim

The invention claimed is:

1. A device for processing at least one biological sample capable of containing at least one target microorganism within at least one container, said device comprising:
at least one displacement device for generating the displacement of the contents of the at least one container;
at least one site for receiving the at least one container, the at least one container being configured to receive the at least one biological sample within the at least one container wherein the site is delimited by a wall fixed on a base and the at least one displacement device, movable with respect to the base, wherein the at least one container comprises a flexible material to allow the at least one container to be compressed against the wall,
wherein the at least one displacement device is movable with respect to the wall to exert a pressure onto the outer surface of the at least one container comprising the flexible material to impose on the at least one container a deformation for generating at least two displacements of the contents of the at least one container at at least two different intensities comprising:
a weakest displacement intensity allowing the homogenization of the at least one biological sample wherein the at least one displacement device is displaced from it/their first position(s) to it/their second position(s), and vice versa, leading the contents of the at least one container to be displaced from a level n, corresponding to a level of the contents at rest, to a homogenization level nh, distinct from the level n, and vice versa and a strongest displacement intensity in a direction of the wall allowing a generation of an increased displacement of the contents to a level n+1, which is different from levels n and nh, such that the contents come into contact with at least one culture, at least one analysis device, or a combination thereof, positioned inside the at least one container, between level n+1 inclusive and level nh exclusive,
wherein the at least one displacement device is selected from a movable arm, a movable blade, a movable wall and a moveable applicator.

2. The device according to claim 1 , said device comprising an optical detection device configured to detect a presence of said at least one target microorganism.

3. The device according to claim 1 , said device comprising a control element configured to alter the at least two different intensities of displacement of the contents.

4. The device according to claim 1 , said device comprising at least one heating element configured to incubate the at least one container.

Assignees

• Biomerieux Sa
• Biomerieux Sa

Inventors

• Baril Florent
• Colin Bruno
• Flandrois Jean-Pierre
• Junillon Thomas
• Mallen Benoît
• Minassian Edgard
• Mosticone David
• Vimont Antoine

Classifications

• C12M41/44

  of volume or liquid level · CPC title

• C12M23/14 Primary

  Bags · CPC title

• G01N33/56911

  Bacteria · CPC title

• C12M27/02

  Stirrer or mobile mixing elements · CPC title

• B01F11/0065

  Operations & Transport · mapped topic