Treatment of greasy skin with a bacterial lystate

Patent metadata

Field	Value
Publication number	US-9782611-B2
Application number	US-60717009-A
Country	US
Kind code	B2
Filing date	Oct 28, 2009
Priority date	Oct 28, 2008
Publication date	Oct 10, 2017
Grant date	Oct 10, 2017

Abstract

The present invention relates to the cosmetic treatment of greasy skin and/or skin that tends to be greasy with a lysate of at least one microorganism of the genus Bifidobacterium species and/or a fraction thereof, as an active.

First claim

The invention claimed is:

1. A method for treating skin, the method comprising:
administering to an individual in need thereof, an effective amount of a whole lysate of at least one microorganism of the genus Bifidobacterium selected from the group consisting of Bifidobacterium longum, Bifidobacterium bifidum; Bifidobacterium breve, Bifidobacterium animalis, Bifidobacterium infantis, Bifidobacterium adolescentis , and Bifidobacterium pseudocatenulatum;
wherein the skin treated is at least one selected from the group consisting of a greasy skin, a skin that tends to be greasy and a skin having a disorder associated with greasy skin or skin that tends to be greasy, and
wherein the whole lysate is obtained by ultrasonic disintegration and comprises released cytoplasmic fractions, fragments of cell wall and metabolic products.

2. The method according to claim 1 , wherein the treated skin has a skin disorder and the skin disorder is a lesion or imperfection of greasy skin or skin that tends to be greasy, a retention lesion of the open comedo type, or a retention lesion of the closed comedo type.

3. The method according to claim 1 , wherein the treated skin has a skin disorder and the skin disorder is at least one skin imperfection selected from the group consisting of sallow, glistening skin, muddy skin, dyschromia, redness, rough skin, and a plaque of dry skin.

4. The method according to claim 1 , wherein the treated skin has a skin disorder and the skin disorder is seborrhoeic dermatosis.

5. A method for controlling seborrhea, the method comprising administering to an individual in need thereof a composition comprising, an effective amount of a whole lysate of at least one microorganism of the genus Bifidobacterium selected from the group consisting of Bifidobacterium longum, Bifidobacterium bifidum, Bifidobacterium breve, Bifidobacterium animalis, Bifidobacterium infantis, Bifidobacterium adolescentis, Bifidobacterium pseudocatenulatum,
wherein the seborrhea is of a greasy skin, a skin that tends to be greasy or a skin having a disorder associated with greasy skin or skin that tends to be greasy, and
wherein the whole lysate is obtained by ultrasonic disintegration and comprises released cytoplasmic fractions, fragments of cell wall and metabolic products.

6. The method according to claim 1 , 4 or 5 , wherein the microorganism of the genus Bifidobacterium is Bifidobacterium longum.

7. The method according to claim 1 , 4 or 5 , wherein a content of active substance(s) in the whole lysate is from 0.1 to 50% by weight.

8. The method according to claim 1 , further comprising:
administering with the whole lysate another microorganism, probiotic or a fraction thereof, different from the whole lysate.

9. The method according to claim 4 , further comprising:
administering with the whole lysate, another microorganism, probiotic or a fraction thereof, different from the whole lysate.

10. The method according to claim 5 , further comprising:
administering with the whole lysate, another microorganism, probiotic or a fraction thereof, different from the whole lysate.

11. The method according to claim 8 , wherein a probiotic microorganism different from the whole lysate is administered and the probiotic microorganism is at least one ascomycete microorganism selected from the group consisting of Saccharomyces, Yarrowia, Kluyveromyces, Torulaspora, Schizosaccharomyces pombe, Debaryomyces, Candida, Pichia, Aspergillus and Penicillium , bacteria of the genus Bacteroides, Fusobacterium, Melissococcus, Propionibacterium, Enterococcus, Lactococcus, Staphylococcus, Peptostreptococcus, Bacillus, Pediococcus, Leuconostoc, Weissella, Aerococcus , and Oenococcus.

12. The method according to claim 9 , wherein a probiotic microorganism different from the whole lysate is administered and the probiotic microorganism is at least one ascomycete microorganism selected from the group consisting of Saccharomyces, Yarrowia, Kluyveromyces, Torulaspora, Schizosaccharomyces pombe, Debaryomyces, Candida, Pichia, Aspergillus and Penicillium , bacteria of the genus Bacteroides, Fusobacterium, Melissococcus, Propionibacterium, Enterococcus, Lactococcus, Staphylococcus, Peptostreptococcus, Bacillus, Pediococcus, Leuconostoc, Weissella, Aerococcus , and Oenococcus.

13. The method according to claim 10 , wherein a probiotic microorganism different from the whole lysate is administered and the probiotic microorganism is at least one ascomycete microorganism selected from the group consisting of Saccharomyces, Yarrowia, Kluyveromyces, Torulaspora, Schizosaccharomyces pombe, Debaryomyces, Candida, Pichia, Aspergillus and Penicillium , bacteria of the genus Bacteroides, Fusobacterium, Melissococcus, Propionibacterium, Enterococcus, Lactococcus, Staphylococcus, Peptostreptococcus, Bacillus, Pediococcus, Leuconostoc, Weissella, Aerococcus , and Oenococcus.

14. The method according to claim 1 , 4 or 5 , wherein the whole lysate is administered topically.

15. The method according to claim 1 , 4 or 5 , wherein the whole lysate is in a composition that is in the form of an aqueous solution, an aqueous-alcoholic solution, an oily solution, a solution dispersion, a lotion dispersion, a serum dispersion, an O/W emulsion, an W/O emulsion, a cream, an aqueous gel, an anhydrous gel, a microemulsion, a microcapsule, a microparticle, or a vesicular dispersion.

Assignees

• Gueniche Audrey
• Castiel Isabelle
• Bernard Dominique
• Oreal

Inventors

• Gueniche Audrey
• Castiel Isabelle
• Bernard Dominique

Classifications

• A61P17/00

  Drugs for dermatological disorders · CPC title

• A61P17/08

  Antiseborrheics · CPC title

• A61P17/10

  Anti-acne agents · CPC title

• A61K8/99 Primary

  from microorganisms other than algae or fungi, e.g. protozoa or bacteria · CPC title

• A61K8/9728

  Fungi, e.g. yeasts · CPC title