Energy efficient high frequency nerve blocking technique

Patent metadata

Field	Value
Publication number	US-9782592-B2
Application number	US-201113184347-A
Country	US
Kind code	B2
Filing date	Jul 15, 2011
Priority date	Jul 15, 2010
Publication date	Oct 10, 2017
Grant date	Oct 10, 2017

Abstract

A neurostimulation system and method of blocking a neural axon. Time-varying electrical energy is conveyed to a blocking site on the neural axon for an initial phase. The conveyed electrical energy has an amplitude and frequency during the initial phase sufficient to block action potentials from propagating along the neural axon from a location proximal to the blocking site to a location distal to the blocking site. The time-varying electrical energy is conveyed to the blocking site on the neural axon for a subsequent phase contiguous with the initial phase. The conveyed electrical energy has a decreased amplitude and a frequency during the subsequent phase sufficient to maintain blocking of the action potentials along the neural axon from the location proximal to the blocking site to the location distal to the blocking site.

First claim

What is claimed is:

1. A method of blocking a neural axon, comprising: conveying time-varying electrical energy to a blocking site on the neural axon for an
initial phase, wherein the conveyed electrical energy has an amplitude and frequency during the initial phase sufficient to block action potentials from propagating along the neural axon from a location proximal to the blocking site to a location distal to the blocking site; and
conveying the time-varying electrical energy to the blocking site on the neural axon for a subsequent phase contiguous with the initial phase, thereby treating pain suffered by a patient, wherein the conveyed electrical energy has, during the subsequent phase, a decreased amplitude relative to the initial phase and a frequency known to maintain blocking of the action potentials along the neural axon from the location proximal to the blocking site to the location distal to the blocking site, wherein the initial phase is in the range of 0.1-20 ms.

2. The method of claim 1 , wherein the amplitude is uniform during the initial phase.

3. The method of claim 1 , wherein the frequency of the conveyed electrical energy is greater than 2 KHz during the initial phase.

4. The method of claim 1 , wherein the frequency of the conveyed electrical energy is in the range of 3 KHz-20 KHz during the initial phase.

5. The method of claim 1 , wherein the time-varying electrical energy is sinusoidal.

6. The method of claim 1 , wherein the subsequent phase is greater than the initial phase.

7. The method of claim 1 , wherein the frequency of the conveyed electrical energy during the subsequent phase is a decreased frequency relative to the initial phase.

8. The method of claim 1 , further comprising applying stimulation pulses to a stimulation site during the initial phase and the subsequent phase to evoke the action potentials at the stimulation site, wherein the stimulation site is proximal to the blocking site.

9. The method of claim 1 , wherein the time-varying electrical energy is conveyed from at least one electrode implanted within a patient to the blocking site.

10. The method of claim 1 , wherein the amplitude is automatically decreased from the initial value at the end of the initial phase to the steady-state value during the subsequent phase.

11. The method of claim 1 , wherein the amplitude of the electrical energy conveyed during the subsequent phase varies, and is, on average, less than the amplitude of the electrical energy conveyed during the initial phase.

12. The method of claim 1 , wherein the subsequent phase is greater than the initial phase.

13. The method of claim 1 , wherein the neural axon is a spinal neural axon.

14. A method of blocking a neural axon, comprising:
conveying time-varying electrical energy to a blocking site on the neural axon for an initial phase, wherein the conveyed electrical energy has an amplitude and frequency during the initial phase sufficient to block action potentials from propagating along the neural axon from a location proximal to the blocking site to a location distal to the blocking site; and
conveying the time-varying electrical energy to the blocking site on the neural axon for a subsequent phase contiguous with the initial phase, thereby treating pain suffered by a patient, wherein the conveyed electrical energy has, during the subsequent phase, a decreased amplitude relative to the initial phase and a frequency known to maintain blocking of the action potentials along the neural axon from the location proximal to the blocking site to the location distal to the blocking site;
wherein the amplitude is decreased from an initial value at the end of the initial phase to a steady-state value during the subsequent phase, the subsequent phase is divided into an amplitude adjustment phase during which the amplitude is gradually decreased from the initial value to the steady-state value at the beginning of a steady-state phase during which the amplitude is maintained at the steady-state value, and the amplitude is exponentially decreased from the initial value to the steady-state value during the amplitude adjustment phase.

15. The method of claim 14 , wherein the amplitude is exponentially decreased in accordance with the equation S=S i *(1−S ss )*e (−λ·(t−t0)) +S ss where t 0 is the time at the beginning of the amplitude adjustment phase, t is the instantaneous time, S is the amplitude of the time-varying electrical energy at any given time t, S i is the amplitude value of the time-varying electrical energy at time t 0 , S ss is the peak steady-state amplitude value of the time-varying electrical energy during the steady-state phase, and A is the time constant that defines the exponential decline of the amplitude of the time-varying electrical energy.

Assignees

• Lee Dongchul
• Boston Scient Neuromodulation Corp

Inventors

• Lee Dongchul

Classifications

• A61N1/0553

  Paddle shaped electrodes, e.g. for laminotomy · CPC title

• A61N1/36171

  Frequency · CPC title

• A61N1/36062

  Spinal stimulation · CPC title

• A61N1/3615 Primary

  Intensity · CPC title

• A61N1/3606

  adapted for a particular treatment · CPC title