Electroporation of tissue products
US-2015343101-A1 · Dec 3, 2015 · US
US9782502B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9782502-B2 |
| Application number | US-201214112250-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 17, 2012 |
| Priority date | Apr 26, 2011 |
| Publication date | Oct 10, 2017 |
| Grant date | Oct 10, 2017 |
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An electron beam sterilization device ( 1 ) for thin-walled containers (C) is fitted with an input ( 40 ) or output unit ( 60 ) provided with a swivelling body to bring a set of containers (C) from the outside environment into the sterilization chamber or vice versa, avoiding radioactive emissions from the sterilization chamber.
Opening claim text (preview).
What is claimed is: 1. A sterilisation device with electron beams for flexible thin wall containers comprising: an input or output unit shielded against radioactive emissions generated by the electron beams and comprising an outer casing and a swivelling body housed at least partially in a compartment inside the outer casing; and a sterilisation group having an inner sterilisation chamber, connected so as to be tight to radioactive emissions downstream of the input unit or upstream of the output unit, comprising at least one electron cannon suitable for emitting a beam of electrons in the sterilisation chamber; wherein the swivelling body is a solid cylindrical body swivelling upon command around a rotation axis and fitted with loading seats to bring a predefined number of containers from an outside environment into the sterilisation chamber, the loadings seats formed in the solid cylindrical body extend radially from the periphery of the solid cylindrical body towards the rotation axis of the solid cylindrical body, wherein remaining solid portions of cylindrical segments brush an inner surface of the compartment inside the outer casing, preventing leaks of radioactive emissions from the sterilisation chamber to the outside environment; wherein the sterilisation chamber comprises a main chamber extending along a first sterilisation axis, and a secondary chamber extending along a second sterilisation axis, incident to the first sterilisation axis; and wherein an emission axis of a second cannon is positioned on an emission plane defined by the emission axis of a first cannon and by a first sterilisation direction, on a side opposite the first cannon in relation to the first sterilisation direction. 2. The sterilisation device according to claim 1 , wherein the swivelling body is fitted with at least two angularly distanced loading seats. 3. The sterilisation device according to claim 2 , wherein the loading seats are positioned diametrically opposite to the rotation axis of the swivelling body. 4. The sterilisation device according to claim 1 , comprising a pre-sterilisation chamber downstream of a loading unit and upstream of the sterilisation group, extending along an input axis, incident to the first sterilisation axis. 5. The sterilisation device according to claim 1 , comprising a post-sterilisation chamber downstream of the sterilisation group, extending along an output axis coincident with the second sterilisation axis. 6. The sterilisation device according to claim 1 , wherein a first cannon is positioned along the first sterilisation axis. 7. The sterilisation device according to claim 6 , wherein a further cannon is positioned along the second sterilisation axis. 8. The sterilisation device according to claim 6 , wherein a second cannon is positioned along the first sterilisation axis. 9. The sterilisation device according to claim 8 , wherein an emission axis of a further cannon is inclined in relation to a second sterilisation direction, in a different way to the emission axis of the first cannon. 10. The sterilisation device according to claim 9 , wherein the emission axis of the second cannon is positioned on an emission plane defined by the emission axis of the first cannon and by a first sterilisation direction, on a side opposite the first cannon in relation to the first sterilisation direction. 11. The sterilisation device according to claim 1 , comprising: a first support, positioned along a first sterilisation direction, suitable for guiding the containers so that they are positioned alongside each other in rows; and a second support, positioned along a second sterilisation direction, suitable for guiding the containers so that they are positioned behind each other in columns. 12. The sterilisation device according to claim 1 , comprising an input unit configured to introduce the containers to be sterilised to the sterilisation group and an output unit configured to remove the sterilised containers from the sterilisation group. 13. A method of sterilising flexible thin wall containers, comprising: providing a sterilisation device with electron beams for flexible thin wall containers; loading containers to be treated in a loading seat of a solid swivelling body of an input unit; rotating the swivelling body to bring the containers into a sterilisation chamber; extracting the containers from the loading seat facing the sterilisation chamber and making them advance along the sterilisation chamber; emitting a cloud of electrons by means of an electron cannon into the sterilisation chamber; and subjecting the containers to sterilisation by the cloud of electrons; wherein the sterilisation device with electron beams for flexible thin wall containers comprises: an input or output unit shielded against radioactive emissions generated by the electron beams and comprising an outer casing and a swivelling body housed at least partially in a compartment inside the outer casing; and a sterilisation group having an inner sterilisation chamber, connected so as to be tight to radioactive emissions downstream of the input unit or upstream of the output unit, comprising at least one electron cannon suitable for emitting a beam of electrons in the sterilisation chamber; wherein the swivelling body is a solid cylindrical body swivelling upon command around a rotation axis and fitted with loading seats to bring a predefined number of containers from an outside environment into the sterilisation chamber, the loadings seats formed in the solid cylindrical body extend radially from the periphery of the solid cylindrical body towards the rotation axis of the solid cylindrical body, wherein remaining solid portions of cylindrical segments brush an inner surface of the compartment inside the outer casing, preventing leaks of radioactive emissions from the sterilisation chamber to the outside environment; wherein the sterilisation chamber comprises a main chamber extending along a first sterilisation axis, and a secondary chamber extending along a second sterilisation axis, incident to the first sterilisation axis; and wherein an emission axis of a second cannon is positioned on an emission plane defined by the emission axis of a first cannon and by a first sterilisation direction, on a side opposite the first cannon in relation to the first sterilisation direction. 14. The method according to claim 13 , comprising the steps of: loading the sterilised containers in a loading seat of a swivelling body of an output unit, the loading seat facing towards the sterilisation chamber; rotating the swivelling body to bring the containers from the sterilisation chamber to an external environment; and extracting the containers from the loading seat facing the external environment. 15. A method of sterilising flexible thin wall containers, comprising the steps of: providing a sterilisation device with electron beams for flexible thin wall containers; inserting the containers in a sterilisation chamber and making them advance along the sterilisation chamber; emitting a cloud of electrons by means of an electron cannon into the sterilisation chamber; subjecting the containers to sterilisation by the cloud of electrons; loading sterilised containers in a loading seat of a swivelling body of an output unit; rotating the swivelling body to bring the containers to an external environment; and extracting the containers from the loading seat facing the external environment and bringing them into the external environment; wherein the sterilisation device with electron beams for flexible thin wall containers compri
Containers other than laboratory or medical, e.g. bottles or mail · CPC title
with provision for relative movement of beam source and object to be irradiated · CPC title
Chambers for sterilisation · CPC title
Sealings, e.g. doors, covers, valves, sluices · CPC title
Apparatus using programmed or automatic operation · CPC title
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