NMR-MAS probe head with integrated transport conduit for an MAS rotor

Patent metadata

Field	Value
Publication number	US-9778331-B2
Application number	US-201414156473-A
Country	US
Kind code	B2
Filing date	Jan 16, 2014
Priority date	Jan 24, 2013
Publication date	Oct 3, 2017
Grant date	Oct 3, 2017

Abstract

An NMR MAS probe head ( 1 ) has an MAS stator ( 7 ) with a base bearing ( 8 ) and a front bearing ( 75 ) for receiving a substance to be measured at a measurement position within an MAS rotor. The front bearing has an opening for inserting the MAS rotor into the space between the base bearing and the front bearing. The opening can be closed by a closing device that, in a loading state, opens and, in a measuring state, closes the opening by means of a movement that is transverse with respect to an axis (a) through the centers of the base bearing and the opening of the front bearing of the MAS stator. This enables automated loading and unloading of the MAS rotor in the space between the base bearing and the front bearing inside the MAS stator in a simple way.

First claim

We claim:

1. A nuclear magnetic resonance (NMR) magic-angle spinning (MAS) probe head for measuring a substance at a measuring position, the probe head comprising:
a tube;
an elongated, substantially circularly cylindrical MAS rotor, said MAS rotor structured for receiving the substance to be measured;
an MAS stator disposed in said tube, wherein said MAS stator has a base bearing and a front bearing having an opening, said MAS stator being disposed, structured and dimensioned for receiving said MAS rotor following insertion thereof from an upward direction into said MAS stator through said opening and into a space between said base bearing and said front bearing, wherein said MAS stator has an axis passing through a center of said base bearing and a center of said opening;
a transport tube for conveying said MAS rotor inside said transport tube, said transport tube extending in an interior of said tube to said MAS stator; and
a gate valve, wherein, in a loading state, said gate valve opens said opening in said MAS stator and, in a measuring state, said gate valve completely closes said opening in said MAS stator, said gate valve thereby being disposed, structured and dimensioned to pass between said loading state and said measuring state by means of a movement that is transverse with respect to said axis of said MAS stator, wherein said gate valve is disposed above said space in which the substance to be measured is located at the measuring position.

2. The probe head of claim 1 , wherein said gate valve has a pneumatic actuator structured to open said opening in said loading state.

3. The probe head of claim 2 , further comprising a pneumatic sample changing system for feeding and removing said MAS rotor to and from said MAS stator.

4. The probe head of claim 3 , wherein said transport tube has a Y-junction device with a blind hole section for intermediate storage of said MAS rotor.

5. The probe head of claim 4 , wherein said blind hole section is constituted in a rocker and said rocker is structured to swivel about a pivot.

6. The probe head of claim 3 , wherein said pneumatic actuator of said closing device is operated with a same compressed air supply as said pneumatic sample changing system.

7. The probe head of claim 1 , wherein the probe head is constituted as a Dewar vessel in a region of said tube.

8. The probe head of claim 1 , wherein said MAS stator is rotatably supported for setting an MAS angle.

9. The probe head of claim 1 , wherein, in said measuring state of said MAS rotor, said gate valve closes said opening with respect to said transport tube and, in said loading state, releases said opening via a movement along a curved trajectory having one component that is transverse and one component that is parallel to said longitudinal axis.

10. The probe head of claim 9 , wherein said gate valve is guided along said curved trajectory on one or more guide pins by means of a guide contour.

11. The probe head of claim 1 , wherein said gate valve contains a pressure element loaded with spring force, which, in said measuring state of the MAS rotor, effects closure of said opening.

12. The probe head of claim 11 , wherein said pressure element is loaded by a compression spring made of non-magnetic material, of CuBe or of spring bronze.

Assignees

• Bruker Biospin Gmbh

Inventors

• Hunkeler Andreas
• Knott Benno
• Osen David

Classifications

• G01R33/307 Primary

  specially adapted for moving the sample relative to the MR system, e.g. spinning mechanisms, flow cells or means for positioning the sample inside a spectrometer · CPC title

• G01R33/31

  Temperature control thereof · CPC title

• G01R33/34092

  RF coils specially adapted for NMR spectrometers · CPC title