Compositions and methods for 3-hydroxypropionic acid production

US9777280B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9777280-B2
Application numberUS-201615060036-A
CountryUS
Kind codeB2
Filing dateMar 3, 2016
Priority dateNov 22, 2010
Publication dateOct 3, 2017
Grant dateOct 3, 2017

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present application discloses genetically modified yeast cells comprising an active 3-HP fermentation pathway, and the use of these cells to produce 3-HP.

First claim

Opening claim text (preview).

What is claimed is: 1. A genetically modified yeast cell selected from the group consisting of I. orientalis, C. lambica , and S. bulderi , the genetically modified yeast cell comprising an active 3-HP fermentation pathway, wherein the cell comprises an exogenous BAAT or gabT gene encoding an enzymatically active polypeptide with at least 85% sequence identity to an amino acid sequence selected from SEQ ID NOs: 20, 21, and 24. 2. The genetically modified yeast cell of claim 1 , wherein the BAAT or gabT gene encodes a polypeptide having at least 90% sequence identity to the amino acid sequence selected from SEQ ID Nos: 20, 21, and 24. 3. The genetically modified yeast cell of claim 1 , wherein the BAAT or gabT gene encodes a polypeptide having at least 95% sequence identity to the amino acid sequence selected from SEQ ID Nos: 20, 21, and 24. 4. The genetically modified yeast cell of claim 1 , wherein the BAAT or gabT gene encodes a polypeptide having at least 97% sequence identity to the amino acid sequence selected from SEQ ID Nos: 20, 21, and 24. 5. The genetically modified yeast cell of claim 1 , wherein the BAAT or gabT gene encodes a polypeptide having at least 98% sequence identity to the amino acid sequence selected from SEQ ID Nos: 20, 21, and 24.

Assignees

Inventors

Classifications

  • C12N1/18Primary

    Baker's yeast; Brewer's yeast · CPC title

  • acting on CH-OH groups as donors (1.1) · CPC title

  • Beta-alanine-pyruvate transaminase (2.6.1.18) · CPC title

  • 4-Aminobutyrate—2-oxoglutarate transaminase (2.6.1.19) · CPC title

  • Aspartate transaminase (2.6.1.1), i.e. aspartate-aminotransferase · CPC title

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Frequently asked questions

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What does patent US9777280B2 cover?
The present application discloses genetically modified yeast cells comprising an active 3-HP fermentation pathway, and the use of these cells to produce 3-HP.
Who is the assignee on this patent?
Cargill Inc, Cargill Inc
What technology area does this patent fall under?
Primary CPC classification C12N1/18. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Oct 03 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).