Molecular probes for multimodality imaging and tracking of stem cells
US-9492571-B2 · Nov 15, 2016 · US
US9775920B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9775920-B2 |
| Application number | US-201615223559-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 29, 2016 |
| Priority date | Jul 31, 2015 |
| Publication date | Oct 3, 2017 |
| Grant date | Oct 3, 2017 |
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The present invention relates to a novel use of N-(4-isopropylphenyl)-5-amino-isoindoline for diagnosing Alzheimer's disease and quantifying amyloid in the brain.
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What is claimed is: 1. A method of diagnosing Alzheimer's disease using a tissue sample from a subject comprising: contacting the tissue sample with a compound labelled with a radioactive element to detect an amyloid in the sample, wherein the compound is represented by Formula (1) below: and detecting the compound bound to the tissue sample. 2. The method according to claim 1 , further comprising quantifying the amount of amylold in the tissue sample. 3. The method according to claim 1 , wherein the radioactive element is C-11 or F-18.
having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil · CPC title
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