Oral care gels

Patent metadata

Field	Value
Publication number	US-9775788-B2
Application number	US-201114356687-A
Country	US
Kind code	B2
Filing date	Nov 15, 2011
Priority date	Nov 15, 2011
Publication date	Oct 3, 2017
Grant date	Oct 3, 2017

Abstract

The invention provides an orally acceptable plaque indicator gel comprising a dye in sufficient concentration to visibly stain plaque upon application, optionally for use in combination with an orally acceptable plaque removal gel comprising an antiplaque agent in sufficient concentration to remove plaque and or kill bacteria upon application, in each case the gel having a specific viscosity permitting efficient application using a pen dispenser, as well as reduced dye or antiplaque agent concentration, together with methods of using the same.

First claim

The invention claimed is:

1. An orally acceptable plaque indicator gel comprising dye in sufficient concentration to visibly stain plaque upon application, wherein the Herschel-Bulkley yield stress is 30 to 45 dynes/cm 2 , the Herschel-Bulkley viscosity is 30 to 45 poise, and the Herschel-Bulkley rate index is 0.5 to 0.6, and wherein the plaque indicator gel comprises about 0.5% xanthan gum and about 1.2% carboxymethyl cellulose, 15-25% glycerin, 15-25% sorbitol, and 50-60% water, and wherein the amount of dye is less than 0.1% by weight of the total formulation.

2. The plaque indicator gel according to claim 1 wherein the elastic modulus (G′) is 200 to 500 dyne/cm 2 and the viscous modulus (G″) is 100-300 dyne/cm 2 .

3. The plaque indicator gel according to claim 1 comprising flavorings selected from saccharin, mint flavor, and combinations thereof.

4. The plaque indicator gel according to claim 1 comprising a surfactant.

5. The plaque indicator gel according to claim 1 comprising a fluoride ion source.

6. The plaque indicator gel according to claim 1 comprising a dye is selected from FD&C Red No. 3, FD&C Blue No. 1, FD&C Violet No. 1, FD&C Green No. 1, FD&C Green No. 2, FD&C Green No. 3, and mixtures thereof.

7. The plaque indicator gel according to claim 1 further comprising an antiplaque agent selected from antibacterial agents and chelating agents.

8. The plaque indicator gel according to claim 1 comprising triclosan.

9. A method of detecting and removing plaque comprising applying a plaque indicator gel according to claim 1 to the teeth of a subject in need thereof, and brushing away the plaque revealed thereby.

10. A method of detecting and removing plaque comprising applying a plaque indicator gel according to claim 1 to the teeth of a subject in need thereof, then applying an orally acceptable plaque removal gel to the teeth in places where the plaque indicator gel indicates the presence of plaque, wherein the plaque removal gel comprises an antiplaque agent in sufficient concentration to remove plaque and/or kill bacteria upon application, and then brushing the teeth.

Assignees

• Chen Elva
• Kennedy Sharon
• Mirajkar Yelloji-Rao
• Jogun Suzanne
• Prencipe Michael
• Colgate Palmolive Co

Inventors

• Chen Elva
• Kennedy Sharon
• Mirajkar Yelloji-Rao
• Jogun Suzanne
• Prencipe Michael

Classifications

• A61K8/731

  Cellulose; Quaternized cellulose derivatives · CPC title

• A61K8/73

  Polysaccharides · CPC title

• A61K8/042 Primary

  Gels · CPC title

• A61K8/345

  containing more than one hydroxy group · CPC title

• A61P1/02

  Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis · CPC title