Biomarker for senescent cells
US-2020371122-A1 · Nov 26, 2020 · US
US9772324B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9772324-B2 |
| Application number | US-201414446298-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 29, 2014 |
| Priority date | Mar 23, 2007 |
| Publication date | Sep 26, 2017 |
| Grant date | Sep 26, 2017 |
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The present invention relates to the use of inhibitors of leukotriene B4 receptor BLT2 for treating asthma. More particularly, the present invention relates to a pharmaceutical composition for treating asthma comprising BLT2 inhibitors and a method for treating asthma using BLT2 inhibitors.
Opening claim text (preview).
What is claimed is: 1. A method for screening an agent for treating asthma, the method comprising the steps of: (a) contacting a lung cell or immune cell containing a long-form BLT2 gene or long-form BLT2 protein with an agent to be screened; and (b) measuring the expression or activity of long-form BLT2, wherein a decrease in the expression or activity of long-form BLT2 indicates the agent can be used for treating asthma, wherein the agent is an antibody or fragment thereof that specifically binds long-form BLT2.
Special therapeutic applications · CPC title
involving specific cell types · CPC title
Double-stranded nucleic acids or oligonucleotides · CPC title
against receptors or cell surface proteins · CPC title
interfering nucleic acids [NA] · CPC title
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