Self-assembled pharmaceutical composition for photodynamic therapy
US-2016089436-A1 · Mar 31, 2016 · US
US9765187B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9765187-B2 |
| Application number | US-201514670805-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 27, 2015 |
| Priority date | Sep 26, 2014 |
| Publication date | Sep 19, 2017 |
| Grant date | Sep 19, 2017 |
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The present invention relates to MRI contrasting agent for contrasting cancer cell which contains ultrafine nanoparticles. More particularly, the present invention is directed to a self-assembled ligand composition comprising a ligand A, which is separated at a specific pH range, and a ligand B of which surface charge changes at a specific pH range, MRI contrast agent for contrasting cancer cell comprising said ligand composition and MRI contrasting nanoparticles, and the methods for preparing them.
Opening claim text (preview).
What is claimed is: 1. A ligand composition for use with a MRI contrasting agent comprising: a ligand A having the following structure: wherein n and m are independently an integer of 5-500, a ligand B having the following structure: wherein n and m are independently an integer of 5-500, wherein at a pH range of 4-7.2, the ligand A is separated from the MRI contrasting agent and the surface charge of ligand B changes from negative to positive.
Polyamides containing oxygen in the form of ether groups (C08G69/12, C08G69/32 take precedence) · CPC title
Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers (involving only carbon-to-carbon unsaturated bond reactions C08F299/00 {; polyester-amides C08G69/44; polyester-imides C08G73/16; polyamides-imides C08G73/14; block- or graft polymers containing polysiloxane sequences C08G77/42}) · CPC title
derived from amino-carboxylic acids · CPC title
the organic macromolecular compound being obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. PLGA · CPC title
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