Column oven and liquid chromatograph

Patent metadata

Field	Value
Publication number	US-9759695-B2
Application number	US-201414455388-A
Country	US
Kind code	B2
Filing date	Aug 8, 2014
Priority date	Aug 27, 2013
Publication date	Sep 12, 2017
Grant date	Sep 12, 2017

Abstract

A column oven includes a main unit, an auxiliary unit, an outside sensor, an internal sensor, a temperature range holding section for holding a plurality of temperature ranges, a temperature range specifying portion for specifying the temperature range to which the outside temperature belongs, a temperature control program holding section for holding a temperature control program for a control method of the main unit and the auxiliary unit in each temperature range in such a way that outputs of the main unit and the auxiliary unit are continuous in the temperature ranges that are adjacent to each other, a control method setting portion for setting a control method of the main unit and the auxiliary unit based on the temperature range specified and the temperature control program, and a temperature control portion for controlling the main unit and the auxiliary unit.

First claim

What is claimed is:

1. A column oven comprising:
a housing including inside a temperature adjusting space for accommodating an analytical column;
a main unit for heating and cooling the analytical column in the temperature adjusting space;
an auxiliary unit, provided separately from the main unit, for heating the analytical column in the temperature adjusting space;
an outside sensor for detecting an outside temperature that is a temperature outside the housing;
an internal sensor for detecting an inside temperature that is a temperature inside the temperature adjusting space;
a set temperature holding section for holding a set temperature that is a target value of a temperature of the analytical column;
a temperature range holding section for holding a plurality of continuous temperature ranges in a temperature scope in which the outside temperature possibly changes;
a temperature range specifying portion for specifying, among the temperature ranges of the temperature range holding section, the temperature range to which the outside temperature detected by the outside sensor belongs;
a temperature control program holding section for holding a temperature control program for a control method of the main unit and the auxiliary unit in each of the temperature ranges in such a way that outputs of the main unit and outputs of the auxiliary unit are continuous as a temperature passes from one of the temperature ranges to an adjacent temperature range;
a control method setting portion for setting a control method of the main unit and the auxiliary unit based on the temperature range specified by the temperature range specifying portion and the temperature control program; and
a temperature control portion for controlling the main unit and the auxiliary unit by using the control method set by the control method setting portion in such a way that the inside temperature is at the set temperature.

2. The column oven according to claim 1 ,
wherein the temperature range holding section includes, as the temperature ranges, a set temperature-neighborhood range that is a temperature range having a specific temperature difference to the set temperature, a first heating range that is a temperature range that is continuous to the set temperature-neighborhood range and that is lower than the set temperature, a second heating range that is a temperature range that is continuous to the first heating range and that is lower than the first heating range, and a cooling range that is a temperature range that is continuous to the set temperature-neighborhood range and that is higher than the set temperature, and
wherein the temperature control program is structured to set, as the control method of the main unit and the auxiliary unit, a fine control method of heating by the auxiliary unit while cooling by the main unit when the temperature range to which the outside temperature belongs is the set temperature-neighborhood range, a first heating control method of stopping outputs of heating and cooling of the main unit and adjusting only a heating output of the auxiliary unit when the temperature range to which the outside temperature belongs is the first heating range, a second heating control method of simultaneously adjusting a heating output of the main unit and the heating output of the auxiliary unit when the temperature range to which the outside temperature belongs is the second heating range, and a cooling control method of stopping the heating output of the auxiliary unit and adjusting only a cooling output of the main unit when the temperature range to which the outside temperature belongs is the cooling range.

3. The column oven according to claim 2 ,
wherein the second heating control method reduces the heating output of the main unit and increases the heating output of the auxiliary unit as the outside temperature rises in the second heating range, in such a way that the heating output of the main unit is zero when the outside temperature is at a boundary temperature between the second heating range and the first heating range.

4. The column oven according to claim 2 ,
wherein the fine control method increases the cooling output of the main unit and reduces the heating output of the auxiliary unit as the outside temperature rises in the set temperature-neighborhood range, in such a way that the heating output of the auxiliary unit is zero when the outside temperature is at a boundary temperature between the set temperature-neighborhood range and the cooling range.

5. The column oven according to claim 2 ,
wherein the temperature range holding section includes, as the temperature range, a third heating range that is a temperature range that is continuous to the second heating range and that is lower than the second heating range, and
wherein, when the temperature range to which the outside temperature belongs is the third heating range, the temperature control program sets, as the control method of the main unit and the auxiliary unit, a third heating control method of adjusting only the heating output of the main unit while stopping the heating output of the auxiliary unit.

6. The column oven according to claim 2 ,
wherein temperature range holding section divides and holds the set temperature-neighborhood range as a first set temperature-neighborhood range that is a temperature range that is lower than the set temperature and a second set temperature-neighborhood range that is a temperature range that is higher than the set temperature, and
wherein the temperature control program sets, as the control method of the main unit and the auxiliary unit, a first fine control method of adjusting the cooling output of the main unit while maintaining constant the heating output of the auxiliary unit when the temperature range to which the outside temperature belongs is the first set temperature-neighborhood range, and a second fine control method of adjusting the heating output of the auxiliary unit while maintaining constant the cooling output of the main unit when the temperature range to which the outside temperature belongs is the second set temperature-neighborhood range.

7. The column oven according to claim 1 , further comprising:
a temperature range setting portion for setting the temperature ranges based on the set temperature, and causing the temperature range holding section to hold the temperature ranges.

8. A liquid chromatograph comprising:
an analytical flow path;
a liquid delivery section for delivering a mobile phase in the analytical flow path;
a sample injection section for injecting a sample into the analytical flow path;
an analytical column, provided on the analytical flow path, on a downstream side of the sample injection section, for separating the sample injected by the sample injection section into components; and
a detector, provided on the analytical flow path, on a downstream side of the analytical column, for detecting a sample component separated by the analytical column,
wherein the analytical column is accommodated inside a temperature adjusting space of a column oven according to claim 1 .

9. The liquid chromatograph according to claim 8 ,
wherein the temperature range holding section includes, as the temperature ranges, a set temperature-neighborhood range that is a temperature range having a specific temperature difference to the set temperature, a first heating range that is a temperature range that is continuous to the set temperature-neighborhood range and that is lower than the set temperature, a second heating range that is a temperature range that is continuous to the first heating range and that is lower than the first heating range, and a cooling range that is a temperature range that is c

Assignees

• Shimadzu Corp

Inventors

• Takahashi Kazuya

Classifications

• F27D19/00

  Arrangements of controlling devices · CPC title

• G01N2030/3007

  same temperature for whole column · CPC title

• F27B5/18

  Arrangement of controlling, monitoring, alarm or like devices · CPC title

• F27B1/26

  Arrangements of controlling devices · CPC title

• F27B17/02

  specially designed for laboratory use · CPC title