Method and integrated device for analyzing liquid flow and liquid-solid interface interaction

Patent metadata

Field	Value
Publication number	US-9759643-B2
Application number	US-201615001321-A
Country	US
Kind code	B2
Filing date	Jan 20, 2016
Priority date	Sep 30, 2014
Publication date	Sep 12, 2017
Grant date	Sep 12, 2017

Abstract

An Integrated Circuit (IC) chip with a lab-on-a-chip, a method of manufacturing the lab-on-a-chip and a method of using the lab-on-a-chip for fluid flow analysis in physical systems through combination with computer modeling. The lab-on-a-chip includes cavities in a channel layer and a capping layer, preferably transparent, covering the cavities. Gates control two dimensional (2D) lattice structures acting as heaters, light sources and/or sensors in the cavities, or fluid channels. The gates and two dimensional (2D) lattice structures may be at the cavity bottoms or on the capping layer. Wiring connects the gates and the 2D lattice structures externally.

First claim

What is claimed is:

1. A method of analyzing fluid flow through a selected body, said method comprising:
collecting data describing physical characteristics for a body;
fabricating a lab-on-a-chip modeling said body from said data, fabricating said lab-on-a-chip comprising:
opening one or more cavities in a channel layer,
forming a capping layer for covering said one or more cavities, said capping layer being transparent,
forming a two dimensional (2D) lattice structure at one surface of each of said one or more cavities, said 2D lattice structure being transparent,
forming a gate at one said surface of at least one cavity, said gate being separated from said at least one cavity by said 2D lattice structure, and
forming wiring connecting the gates and the 2D lattice structures externally;

adding fluid to said cavity;
selectively connecting biases, signals and sensors to said wiring;
causing light to pass through said fluid;
measuring fluid flow responses to said biases, signals and light.

2. A method as in claim 1 , wherein said capping layer includes at least one input/output port above at least one cavity, said input/output port for introducing said fluid into, and removing said fluid from, said cavity.

3. A method as in claim 1 , wherein biasing said gates and said 2D lattice structures causes one or more of said 2D lattice structures to generate said light being measured to pass through said fluid.

4. A method as in claim 1 , wherein biasing said gates and said 2D lattice structures causes one or more of said 2D lattice structures to heats said fluid, an optical wave guide providing said light being measured to one surface of said lab-on-a-chip, said light exiting an opposite surface of said lab-on-a-chip to a detector at said opposite surface.

5. A method as in claim 1 , wherein said body is a hydrocarbon reservoir, said one or more cavities including one or more structural features representative of the physical properties of said hydrocarbon reservoir, said one or more structural features obstructing fluid flow through said cavity.

6. A method as in claim 1 , wherein at least one said 2D lattice structure is a local heater selectively heating said fluid at said at least one 2D lattice structure.

7. A method as in claim 1 , wherein said body is a biological body.

Assignees

• IBM

Inventors

• Avouris Phaedon
• Engel Michael
• Feger Claudius
• Giro Ronaldo
• Ferreira Rodrigo
• Steiner Mathias

Classifications

• G01N33/24

  Earth materials (G01N33/42 takes precedence) · CPC title

• G01N11/04 Primary

  through a restricted passage, e.g. tube, aperture · CPC title

• G06F30/392

  Floor-planning or layout, e.g. partitioning or placement · CPC title

• G01N21/71

  thermally excited · CPC title

• G01N2011/008

  optical properties · CPC title