BAX agonist, compositions, and methods related thereto
US-9402850-B2 · Aug 2, 2016 · US
US9758468B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9758468-B2 |
| Application number | US-201615293507-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 14, 2016 |
| Priority date | Dec 25, 2012 |
| Publication date | Sep 12, 2017 |
| Grant date | Sep 12, 2017 |
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The present invention provides a halogenated aniline represented by formula (I) (wherein each of X 1 and X 2 independently represents a chlorine atom, a bromine atom or an iodine atom), a method for producing the halogenated aniline, and other aspects.
Opening claim text (preview).
The invention claimed is: 1. A method for producing a halogenated nitrobenzene, comprising: a step of halogenating 1,2-difluorobenzene or a 1-halogeno-3,4-difluorobenzene to obtain a halogenated benzene represented by formula (III): wherein each of X 1 and X 2 independently represents a chlorine atom, a bromine atom or an iodine atom, and a step of subsequently nitrating the halogenated benzene to obtain a halogenated nitrobenzene represented by formula (II): wherein each of X 1 and X 2 independently represents a chlorine atom, a bromine atom or an iodine atom. 2. The method for producing a halogenated nitrobenzene according to claim 1 , wherein fuming sulfuric acid and concentrated nitric acid are added to the halogenated benzene represented by formula (III) to nitrate the halogenated benzene. 3. The method for producing a halogenated nitrobenzene according to claim 1 , wherein fuming sulfuric acid and fuming nitric acid are added to the halogenated benzene represented by formula (III) to nitrate the halogenated benzene.
by formation of nitro groups together with reactions not involving the formation of nitro groups · CPC title
the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups · CPC title
by reduction of nitro groups · CPC title
containing fluorine · CPC title
the six-membered aromatic ring or a condensed ring system containing that ring being substituted by halogen atoms · CPC title
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