Apparatus for hermetically sealed storage of liquids for a microfluidic system

Patent metadata

Field	Value
Publication number	US-9757724-B2
Application number	US-201113985784-A
Country	US
Kind code	B2
Filing date	Dec 28, 2011
Priority date	Feb 15, 2011
Publication date	Sep 12, 2017
Grant date	Sep 12, 2017

Abstract

An apparatus for hermetically sealed storage of liquids for a microfluidic system includes at least one cavity and at least one sealing cone. A connection to the microfluidic system is established via the at least one sealing cone. Additionally, the at least one sealing cone is configured to close the at least one cavity.

First claim

The invention claimed is:

1. A device for hermetically sealed storage of liquids for a microfluidic system, comprising:
at least one cavity formed in the device, the at least one cavity being configured to receive a fluid; and
at least one sealing cone, in a first configuration the at least one sealing cone being arranged between and separating the at least one cavity from a channel in the microfluidic system, and in a second configuration the at least one sealing cone providing a passage through the at least one sealing cone that fluidically connects the at least one cavity and the channel of the microfluidic system,
wherein the at least one sealing cone is shaped as a protuberance.

2. The device as claimed in claim 1 , wherein the at least one cavity has in its entirety, or in parts thereof, one or more of a channel structure and a blister structure.

3. The device as claimed in claim 1 , wherein the at least one cavity is formed from at least two parts that are connected to each other in partial surfaces, and wherein the parts are chosen from the group comprising polymer film, polymer sheet, and elastomeric membrane.

4. The device as claimed in claim 1 , wherein the at least one cavity has a volume of 10 μl to 10 ml.

5. The device as claimed in claim 1 , wherein the at least one cavity is configured to receive reagents as fluid.

6. The device as claimed in claim 1 , wherein the at least one cavity is configured to receive a sample that is to be analyzed as fluid.

7. The device as claimed in claim 1 , wherein:
the at least one cavity serves as a waste reservoir after being emptied of the fluid.

8. The device as claimed in claim 7 , wherein the waste reservoir contains an absorption material.

9. The device as claimed in claim 1 , wherein the at least one cavity has a filling opening.

10. The device as claimed in claim 9 , wherein the filling opening is closed by a stopper, a mash weld, a clip, a seal, or an adhesive tape.

11. The device as claimed in claim 1 , wherein the at least one cavity has a venting opening.

12. The device as claimed in claim 1 , wherein the sealing cone comprises at least one of the following components via which a connection is configured to be established between the sealing cone and the microfluidic system: a predetermined breaking point, a pin, an elastomeric seal, and film.

13. The device as claimed in claim 3 , wherein the at least two parts are welded or adhesively bonded to each other.

14. The device as claimed in claim 4 , wherein the at least one cavity has a volume of 20 μl to 5 ml.

15. The device as claimed in claim 4 , wherein the at least one cavity has a volume of 200 μl to 1 ml.

16. The device as claimed in claim 8 , wherein the absorption material is superabsorbent particles or fibers.

17. The device as claimed in claim 9 , wherein the filling opening is a funnel-shaped filling nozzle.

18. The device as claimed in claim 1 , wherein the at least one cavity is filled with the fluid and emptied of the fluid via the at least one sealing cone.

19. The device as claimed in claim 18 , wherein the at least one cavity is filled with the fluid and emptied of the fluid only via the at least one sealing cone.

20. The device as claimed in claim 7 , wherein the at least one cavity includes at least one of:
at least one cavity configured to receive reagents as fluid; and
at least one cavity in which a sample that is to be analyzed is received as fluid.

Assignees

• Rothacher Peter
• Dorrer Christian
• Bosch Gmbh Robert

Inventors

• Rothacher Peter
• Dorrer Christian

Classifications

• B01L3/563

  Joints or fittings; Separable fluid transfer means to transfer fluids between at least two containers, e.g. connectors · CPC title

• B01L3/523

  with means for closing or opening · CPC title

• B01L3/502738

  characterised by integrated valves (throttle valves in microfluidic sample containers B01L3/502746) · CPC title

• B01L3/565

  Seals · CPC title

• Y10T436/2575

  Volumetric liquid transfer · CPC title