Eye mounted device for therapeutic agent release
US-12167978-B2 · Dec 17, 2024 · US
US9757563B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9757563-B2 |
| Application number | US-201514880830-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 12, 2015 |
| Priority date | Jan 26, 2005 |
| Publication date | Sep 12, 2017 |
| Grant date | Sep 12, 2017 |
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The present invention is a method of improving the persistence of electrical neural stimulation, and specifically a method of improving the persistence of an image supplied to a retina, or visual cortex, through a visual prosthesis. A continuously stimulated retina, or other neural tissue, will desensitize after a time period in the range of 20 to 150 seconds. However, an interruption of the stimulation on the order of a few milliseconds will restore the retinal sensitivity without the user perceiving the interruption, or with the user barely perceiving the interruption.
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The invention claimed is: 1. A method of neural stimulation comprising: stimulating neural tissue according to input stimuli by activating electrodes individually or in groups according to a predetermined pattern, wherein the pattern results in interrupting each electrode for a period shorter than the threshold of perception but of sufficient length of time to restore neural sensitivity, and not interrupting all electrodes simultaneously. 2. The method according to claim 1 , wherein said predetermined pattern is a pseudorandom pattern. 3. The method according to claim 1 , wherein the predetermined pattern is a raster pattern. 4. The method according to claim 1 , wherein the predetermined pattern jumps around to avoid sequentially activating geographically nearby electrodes. 5. The method according to claim 1 , wherein modifying stimulation on an electrode is reducing stimulation. 6. The method according to claim 1 , wherein modifying stimulation on an electrode is not stimulating on the electrode. 7. The method according to claim 1 , wherein modifying stimulation is for a period shorter than the threshold of perception. 8. The method according to claim 1 , wherein the duration of modifying is programmable.
of the eye · CPC title
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