Electrophysiology system and methods

Patent metadata

Field	Value
Publication number	US-9757191-B2
Application number	US-201414498211-A
Country	US
Kind code	B2
Filing date	Sep 26, 2014
Priority date	Jan 10, 2012
Publication date	Sep 12, 2017
Grant date	Sep 12, 2017

Abstract

An electrophysiology system comprises an ablation catheter, a radiofrequency generator, and a mapping processor. The ablation catheter has a tissue ablation electrode and a plurality of microelectrodes distributed about the circumference of the tissue ablation electrode and electrically isolated therefrom. The plurality of microelectrodes define a plurality of bipolar microelectrode pairs. The mapping processor is configured to acquire output signals from the bipolar microelectrode pairs, compare the output signals, and generate an output to a display providing a visual indication of a characteristic of the microelectrodes and the tissue ablation electrode relative to myocardial tissue to be mapped and/or ablated.

First claim

We claim:

1. An electrophysiology method comprising:
advancing a distal portion of an ablation catheter intravascularly to a location proximate myocardial tissue within a chamber of a heart, the distal portion of the ablation catheter including:
a tissue ablation electrode configured to apply ablation energy to the myocardial tissue;
a plurality of microelectrodes circumferentially distributed about the tissue ablation electrode and electrically isolated therefrom, the plurality of microelectrodes defining a plurality of bipolar microelectrode pairs, each bipolar microelectrode pair configured to generate an output signal based on a cardiac activation signal;

acquiring the output signals from each of the bipolar microelectrode pairs;
comparing an amplitude of the output signal from each of the bipolar microelectrode pairs to the amplitudes of the output signals from the other of the plurality of bipolar microelectrode pairs; and
displaying to a clinician a visual indication of a proximity of the tissue ablation electrode to the myocardial tissue, the visual indication including:
an indication that the tissue ablation electrode is in contact with the myocardial tissue if, based on the comparison between the amplitudes of the output signals, a difference between the amplitude of any one of the output signals and the amplitude of any one or more of the other output signals exceeds a predetermined threshold; and
an indication that the tissue ablation electrode is not in contact with the myocardial tissue if, based on the comparison between the amplitudes of the output signals, the difference between the amplitude of any one of the output signals and the amplitude of any one or more of the other output signals does not exceed a predetermined threshold.

2. The method of claim 1 , wherein the acquiring and comparing steps are performed by a mapping processor operatively coupled to the microelectrodes.

3. The method of claim 1 , wherein the plurality of microelectrodes include three microelectrodes defining first, second and third bipolar microelectrode pairs.

4. The method of claim 3 , wherein the three microelectrodes are disposed at the same longitudinal position along the tissue ablation electrode.

5. The method of claim 4 , further comprising displaying to the clinician a visual indication of an orientation of the tissue ablation electrode relative to the myocardial tissue based on the amplitudes of the output signals from the first, second and third bipolar microelectrode pairs.

6. The method of claim 5 , wherein the ablation catheter further comprises a plurality of irrigation ports in the tissue ablation electrode fluidly and operatively coupled to an irrigation fluid reservoir and pump.

7. The method of claim 1 , wherein the ablation catheter further includes a proximal handle having a control element for manipulation by a user, and wherein advancing the distal portion of the ablation catheter includes manipulating the control element to deflect the distal portion for positioning the tissue ablation electrode adjacent to the myocardial tissue.

8. An electrophysiology method comprising:
acquiring signals indicative of bioelectrical cardiac activity from bipolar pairs of microelectrodes of a plurality of microelectrodes, the plurality of microelectrodes circumferentially distributed around a tissue ablation electrode and electrically isolated therefrom, the tissue ablation electrode mounted on a catheter and configured to apply ablation energy to the myocardial tissue;
comparing an amplitude of the signal from each of the bipolar microelectrode pairs to the amplitudes of the signals from the other of the plurality of bipolar microelectrode pairs; and
displaying to a clinician a visual indication of a proximity of the tissue ablation electrode to the myocardial tissue, the visual indication including:
an indication that the tissue ablation electrode is in contact with the myocardial tissue if, based on the comparison between the amplitudes of the output signals, a difference between the amplitude of any one of the output signals and the amplitude of any one or more of the other output signals exceeds a predetermined threshold; and
an indication that the tissue ablation electrode is not in contact with the myocardial tissue if, based on the comparison between the amplitudes of the output signals, the difference between the amplitude of any one of the output signals and the amplitude of any one or more of the other output signals does not exceed a predetermined threshold.

9. The method of claim 8 , wherein the acquiring and comparing steps are performed by a mapping processor operatively coupled to the microelectrodes.

10. The method of claim 8 , wherein the plurality of microelectrodes include three microelectrodes defining first, second and third bipolar microelectrode pairs.

11. The method of claim 10 , wherein the three microelectrodes are disposed at the same longitudinal position along the tissue ablation electrode.

12. The method of claim 11 , further comprising displaying to the clinician a visual indication of an orientation of the tissue ablation electrode relative to the myocardial tissue based on the amplitudes of the output signals from the first, second and third bipolar microelectrode pairs.

13. The method of claim 8 , wherein the ablation catheter further comprises a plurality of irrigation ports in the tissue ablation electrode fluidly and operatively coupled to an irrigation fluid reservoir and pump.

Assignees

• Boston Scient Scimed Inc
• Boston Scient Scimed Inc

Inventors

• Avitall Boaz
• Koblish Josef V

Classifications

• A61B2018/00898

  Alarms or notifications created in response to an abnormal condition · CPC title

• A61B5/6852

  Catheters · CPC title

• A61B2218/002

  Irrigation · CPC title

• A61B18/18

  by applying electromagnetic radiation, e.g. microwaves · CPC title

• A61B2018/00678

  upper · CPC title