Multiphase oral care compositions

Patent metadata

Field	Value
Publication number	US-9750825-B2
Application number	US-201114365113-A
Country	US
Kind code	B2
Filing date	Dec 16, 2011
Priority date	Dec 16, 2011
Publication date	Sep 5, 2017
Grant date	Sep 5, 2017

Abstract

Described herein are dentifrices comprising a first formulation and a second formulation, wherein the formulations are coaxially extruded, so that the first formulation enrobes the second formulation, wherein the first formulation is opaque and wherein the second formulation comprises dissolvable film fragments, together with methods of making and using the same and containers for providing the same.

First claim

The invention claimed is:

1. A dentifrice comprising a first formulation and a second formulation, wherein the formulations are coaxially extruded, so that the first formulation enrobes the second formulation, wherein the first formulation is opaque and wherein the second formulation comprises dissolvable film fragments;
wherein the film fragments are stable in the formulation but disintegrate during use of the dentifrice and wherein the film fragments comprise a pigment that is released upon disintegration of the film fragments during use of the dentifrice;
and wherein the film fragments comprise by dry weight of the film, 20-60% cellulose ethers, 10-30% propylene glycol, 1-5% polysorbate 80, and 15-55% pigment; and wherein the film fragments are single layer film fragments.

2. The dentifrice of claim 1 wherein the cellulose ether is selected from the group consisting of an alkylcellulose, a hydroxyalkyl cellulose, and a combination of two or more thereof.

3. The dentifrice of claim 1 wherein the film fragments further comprise a starch.

4. The dentifrice of claim 1 wherein the film fragments are substantially dissolved after a period of greater than 30 seconds and less than 180 seconds of brushing in the presence of water, thereby providing a color signal to the user of adequate brushing.

5. The dentifrice of claim 1 wherein the average thickness of the film fragments is 0.5-5 mils.

6. The dentifrice of claim 1 wherein the cellulose ethers are selected from the group consisting of methyl cellulose, hydroxypropylmethyl cellulose, and mixtures thereof.

7. The dentifrice of claim 1 further comprising one or more of water, abrasives, surfactants, foaming agents, vitamins, polymers, enzymes, humectants, thickeners, antimicrobial agents, preservatives, flavorings, colorings and/or combinations thereof.

8. The dentifrice of claim 1 wherein the first formulation has a water activity higher than the water activity of the second formulation.

9. A dentifrice comprising a first formulation and a second formulation, wherein the formulations are coaxially extruded, so that the first formulation enrobes the second formulation, wherein the first formulation comprises dissolvable film fragments and the second formulation is opaque.

10. A toothpaste container capable of co-axial extrusion of a first dentifrice formulation which is opaque and a second dentifrice formulation which comprises film fragments, such that upon extrusion, the first formulation enrobes the second formulation, to provide a dentifrice according to claim 1 , the toothpaste container having
an aperture,
a first zone or compartment within the container containing the first dentifrice formulation, and
a second zone or compartment within the container containing the second dentifrice formulation,
wherein the aperture is adapted for coaxial extrusion and has an outer opening in fluid communication with the first zone or compartment, said outer opening being coaxially oriented around a central opening in fluid communication with the second zone or compartment, and
wherein the volume of the first and second zones or compartments can be reduced,
such that when the volume of first and second zones or compartments is reduced, the first and second formulations are coaxially extruded from the aperture.

11. A method of cleaning the teeth comprising brushing with a dentifrice according to claim 1 wherein the film fragments comprise a pigment and brushing is continued until the film fragments dissolve and the pigment provides a color signal to the user of adequate brushing.

12. A method of making a dentifrice according to claim 1 comprising coaxially extruding a first formulation and a second formulation, so that the first formulation enrobes the second formulation.

Assignees

• Szewczyk Gregory
• Patel Neeta Atul
• Jogun Suzanne
• Prencipe Michael
• Colgate Palmolive Co

Inventors

• Szewczyk Gregory
• Patel Neeta Atul
• Jogun Suzanne
• Prencipe Michael

Classifications

• A61K8/4993

  Derivatives containing from 2 to 10 oxyalkylene groups · CPC title

• A61K8/731

  Cellulose; Quaternized cellulose derivatives · CPC title

• A61K49/00 Primary

  Preparations for testing in vivo · CPC title

• A61K8/0233

  Distinct layers, e.g. core/shell sticks · CPC title

• A61K2800/43

  Pigments; Dyes · CPC title