Lipids for Therapeutic Agent Delivery Formulations
US-2016074514-A1 · Mar 17, 2016 · US
US9745251B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9745251-B2 |
| Application number | US-201314413875-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 7, 2013 |
| Priority date | Jul 11, 2012 |
| Publication date | Aug 29, 2017 |
| Grant date | Aug 29, 2017 |
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The invention relates to novel compounds, to aqueous, in particular surfactant-containing formulations containing the novel compounds and to the use of the novel compounds as thickening agents of aqueous, in particular surfactant-containing formulations.
Opening claim text (preview).
The invention claimed is: 1. An aqueous formulation comprising a compound of formula (I) wherein R 1 and R 2 of the compound of formula (I) are selected from one of the following groupings R 1 ═H or 2-hydroxypropyl and R 2 =2-hydroxypropyl; R 1 ═H or 2-aminoethyl and R 2 =2-aminoethyl; R 1 ═H or N-(2-hydroxyethyl)aminoethyl and R 2 ═N-(2-hydroxyethyl)aminoethyl; R 1 ═H or 2-(2-hydroxyethoxy)ethyl and R 2 =2-(2-hydroxyethoxy)ethyl; R 1 =methyl or 2,3,4,5,6-pentahydroxyhexyl and R 2 =2,3,4,5,6-pentahydroxyhexyl; and R 1 ═H or 2-(1-piperazinyl)ethyl and R 2 =2-(1-piperazinyl)ethyl. 2. The aqueous formulation of claim 1 , wherein R 1 ═H and R 2 ═N-(2-hydroxyethyl)aminoethyl. 3. The aqueous formulation according to claim 1 , wherein said aqueous formulation further comprises at least one surfactant. 4. The aqueous formulation according to claim 3 , wherein the at least one surfactant is a mixture of at least one anionic surfactant and at least one nonionic surfactant. 5. The aqueous formulation according to claim 3 , wherein the at least one surfactant is a biosurfactant selected from rhamnolipids, sophorolipids, trehalose- and other mycolic-acid-containing glycolipids, and also cellobiose and mannosylerythritol lipids. 6. The aqueous formulation according to claim 1 , wherein said aqueous formulation further comprises at least one enzyme. 7. The aqueous formulation according to claim 1 , wherein said at least one compound of formula (I) is present in an amount of from 0.1% by weight to 50% by weight, where the % by weight refers to the total formulation.
having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups · CPC title
Mixtures · CPC title
having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms · CPC title
Colloidal solutions, e.g. gels; Thixotropic solutions or pastes · CPC title
Amides · CPC title
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