Metallorganocatalysis for asymmetric transformations

Patent metadata

Field	Value
Publication number	US-9744528-B2
Application number	US-201414775159-A
Country	US
Kind code	B2
Filing date	Mar 11, 2014
Priority date	Mar 11, 2013
Publication date	Aug 29, 2017
Grant date	Aug 29, 2017

Abstract

A ligand having the structure or its enantiomer; (I) wherein: each one of R a , R b , R c and R d is selected from alkyl, cycloalkyl, and aryl; the bridge group is selected from CH 2 NH; *CH(CH 3 )NH(C*,R); and the organocatalyst is an organic molecule catalyst covalently bound to the bridge group. Also, a catalyst having the structure or its enantiomer: (II) wherein: each one of R a , R b , R c and R d is selected from alkyl, cycloalkyl, and aryl; the bridge group is selected from CH 2 NH; *CH(CH 3 )NH(C*,R); and *CH(CH 3 )NH(C*,S); the organocatalyst is an organic molecule catalyst covalently bound to the bridge group; and M is selected from the group consisting of Rh, Pd, Cu, Ru, Ir, Ag, Au, Zn, Ni, Co, and Fe.

First claim

What is claimed is:

1. A ligand selected from the group consisting of compounds represented by the following formulae:

2. A ligand selected from the group consisting of compounds represented by the following formulae:

wherein R in the moiety —PR 2 is selected from the group consisting of phenyl; 4-CH 3 -phenyl; 3,5-(CH 3 ) 2 -phenyl; 3,5-(t-butyl) 2 -phenyl; 3,5-(CF 3 ) 2 -phenyl; 2-CH 3 -phenyl; C 6 F 5 ; 2-naphthyl; 1-naphthyl; t-butyl; i-propyl; cyclohexyl and cyclopentyl.

Assignees

• Univ Rutgers

Inventors

• Zhang Xumu

Classifications

• B01J31/2409 Primary

  with more than one complexing phosphine-P atom · CPC title

• B01J2531/821

  Ruthenium · CPC title

• B01J2531/16

  Copper · CPC title

• B01J2531/827

  Iridium · CPC title

• B01J2531/822

  Rhodium · CPC title