System and methods for lung isolation and one lung ventilation

Patent metadata

Field	Value
Publication number	US-9744323-B2
Application number	US-201414560873-A
Country	US
Kind code	B2
Filing date	Dec 4, 2014
Priority date	Jun 15, 2012
Publication date	Aug 29, 2017
Grant date	Aug 29, 2017

Abstract

A lung isolation system configured for selective isolation and ventilation of the lung in conjunction with a standard endotracheal tube. The system includes an expandable bronchial isolation tube comprising a collapsible nitinol frame, a bifurcated adapter, and a steerable optical stylet.

First claim

What is claimed is:

1. An apparatus for lung isolation and selective lung ventilation, comprising:
an expandable bronchial isolation tube (EBIT) having a central channel spanning from a proximal end and a distal end of the tube;
wherein the EBIT comprises a collapsible tubular member terminating at said distal end;
the collapsible tubular member having a collapsed configuration and an open tubular configuration, wherein the tubular member collapses in response to applying an axial load and opens in response to removing the axial load;
wherein the distal end of the EBIT comprises an expandable member having a compressed configuration and an expanded configuration;
wherein the expandable member is configured to engage an internal surface at a location within a patient's airway when in the expanded configuration; and
a bifurcated connector having a distal section configured for attachment to an endotracheal tube;
said distal section bifurcating into two proximal lumens;
wherein a first lumen of the two proximal lumens is configured to receive the EBIT in the collapsed configuration for to advancement past the endotracheal tube to the location; and
wherein, upon opening of the collapsible tubular member and engagement of the expandable member at the location, ventilation is applied to either of the two proximal lumens to selectively ventilate the patient's left and right lungs.

2. An apparatus as recited in claim 1 , further comprising:
a steerable stylet;
wherein the steerable stylet is configured to be received within the central channel of the EBIT such that the EBIT can be collapsed around the stylet for delivery to the location; and
wherein the steerable stylet is configured to steer the EBIT to the location within patient's airway.

3. An apparatus as recited in claim 2 , wherein the steerable stylet comprises an optical steerable stylet having a distal end with a camera disposed on the distal end of the stylet.

4. An apparatus as recited in claim 1 , wherein the collapsible tubular member comprises a collapsible nitinol frame configured to spring to the open tubular configuration when in a resting state, and a membrane configured to conduct gas through the central channel.

5. An apparatus as recited in claim 1 , wherein the expandable member comprises a cylindrical balloon having an outer surface configured to engage the internal surface of the airway to affect a seal with the internal surface.

6. An apparatus as recited in claim 5 , wherein the outer surface of the cylindrical balloon is course to promote contact with the internal surface of the airway.

7. An apparatus as recited in claim 1 , wherein the first lumen comprises an internal seal configured to mate with the EBIT when in the open tubular configuration.

8. An apparatus as recited in claim 7 , wherein the proximal end of the EBIT comprises a connector configured to allow attachment of a ventilator.

9. An apparatus as recited in claim 8 , wherein a second lumen of the two proximal lumens comprises a connector configured to allow attachment of a ventilator.

10. An apparatus as recited in claim 9 :
wherein the expandable member is configured to engage a bronchus wall of the airway;
wherein attachment of a ventilator to the proximal end of the EBIT ventilates a lung in communication with the engaged bronchus; and
wherein attachment of a ventilator to the second lumen ventilates a lung in communication with a bronchus not engaged by the expandable member.

11. A system for lung isolation and selective lung ventilation, comprising:
an expandable bronchial isolation tube (EBIT) having a central channel spanning from a proximal end and a distal end of the tube;
wherein the EBIT comprises a collapsible tubular member terminating at said distal end;
the collapsible tubular member having a collapsed configuration and an open tubular configuration, wherein the tubular member collapses in response to applying an axial load and opens in response to removing the axial load;
wherein the distal end of the EBIT comprises an expandable member having a compressed configuration and an expanded configuration;
wherein the expandable member is configured to engage an internal surface at a location within a patient's airway when in the expanded configuration;
a bifurcated connector having a distal section configured for attachment to an endotracheal tube;
said distal section bifurcating into two proximal lumens;
wherein a first lumen of the two proximal lumens is configured to receive the EBIT in the collapsed configuration for advancement past the endotracheal tube to the location;
wherein, upon opening of the collapsible tubular member and engagement of the expandable member at the location, ventilation is applied to either of the two proximal lumens to selectively ventilate the patient's left and right lungs; and
a steerable stylet;
wherein the steerable stylet is configured to be received within the central channel of the EBIT such that the EBIT can be collapsed around the stylet for delivery to the location; and
wherein the steerable stylet is configured to steer the EBIT to the location within patient's airway.

12. A system as recited in claim 11 , wherein the steerable stylet comprises an optical steerable stylet having a distal end with a camera disposed on the distal end of the stylet.

13. A system as recited in claim 11 , wherein the collapsible tubular member comprises a collapsible nitinol frame configured to spring to the open tubular configuration when in a resting state, and a membrane configured to conduct gas through the central channel.

14. A system as recited in claim 11 , wherein the expandable member comprises a cylindrical balloon having an outer surface configured to engage the internal surface of the airway to affect a seal with the internal surface.

15. A system as recited in claim 14 , wherein the outer surface of the cylindrical balloon is course to promote contact with the internal surface of the airway.

16. A system as recited in claim 11 , wherein the first lumen comprises an internal seal configured to mate with the EBIT when in the open tubular configuration.

17. A system as recited in claim 16 , wherein the proximal end of the EBIT comprises a connector configured to allow attachment of a ventilator.

18. A system as recited in claim 17 , wherein a second lumen of the two proximal lumens comprises a connector configured to allow attachment of a ventilator.

19. A system as recited in claim 18 :
wherein the expandable member is configured to engage a bronchus wall of the airway;
wherein attachment of a ventilator to the proximal end of the EBIT ventilates a lung in communication with the engaged bronchus; and
wherein attachment of a ventilator to the second lumen ventilates a lung in communication with a bronchus not engaged by the expandable member.

20. A method for lung isolation and selective lung ventilation; comprising:
inserting a distal end of an endotracheal tube into an airway of the patient;
coupling a distal section of a bifurcated connector to a proximal end of the endotracheal tube, the distal section bifurcating into two proximal lumens;
receiving an expandable bronchial isolation tube (EBIT) in a collapsed configuration through a first lumen of the two proximal lumens and advancing the EBIT past the distal end endotracheal tube to a location within the airway;
opening the EBIT to an open tubular configuration;
wherein the EBIT collapses in response to applying an axial load and opens in resp

Assignees

• Univ California

Inventors

• Hoftman Nir N
• Mahajan Aman

Classifications

• A61M16/0459

  one cuff behind another · CPC title

• A61B1/05

  characterised by the image sensor, e.g. camera, being in the distal end portion · CPC title

• A61M16/0443

  Special cuff-wall materials (A61M16/0481, A61M16/0422 take precedence) · CPC title

• A61M16/0404 Primary

  with means for selective or partial lung respiration · CPC title

• A61M16/0463

  combined with suction tubes, catheters or the like; Outside connections · CPC title