Vaccines and immunotherapeutics using IL-28 and compositions and methods of using the same

US9744229B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9744229-B2
Application numberUS-201414263752-A
CountryUS
Kind codeB2
Filing dateApr 28, 2014
Priority dateApr 4, 2008
Publication dateAug 29, 2017
Grant dateAug 29, 2017

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Abstract

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Compositions, recombinant vaccines and live attenuated pathogens comprising one or more isolated nucleic acid molecules that encode an immunogen in combination with an isolated nucleic acid molecule that encodes IL-28 or a functional fragment thereof are disclosed. Methods of inducing an immune response in an individual against an immunogen, using such compositions are disclosed.

First claim

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The invention claimed is: 1. A method of inducing an immune response in an individual against an immunogen comprising administering to said individual a composition comprising an isolated nucleic acid molecule that encodes an immunogen and an isolated nucleic acid molecule that encodes a codon-optimized IL-28B or functional fragment thereof, having an IgE signal peptide. 2. The method of claim 1 , wherein the immunogen is a viral protein. 3.…

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What does patent US9744229B2 cover?
Compositions, recombinant vaccines and live attenuated pathogens comprising one or more isolated nucleic acid molecules that encode an immunogen in combination with an isolated nucleic acid molecule that encodes IL-28 or a functional fragment thereof are disclosed. Methods of inducing an immune response in an individual against an immunogen, using such compositions are disclosed.
Who is the assignee on this patent?
Univ Pennsylvania
What technology area does this patent fall under?
Primary CPC classification C07K14/54. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Aug 29 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).